Handbook of CH-Functionalization 2022
DOI: 10.1002/9783527834242.chf0036
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Ru‐Catalyzed CH Activations with Oxidizing Directing Groups

Abstract: Transition metal‐catalyzed CH bond activation has emerged as a powerful and ideal method for organic synthesis in recent decades. To avoid the use of over‐stoichiometric oxidant, the concept of oxidizing directing group was introduced for different catalytic systems. Recently, such strategy has been widely employed in the ruthenium‐catalyzed reactions, enabling novel CH functionalization under relatively mild conditions. In this article, progress in the recent development of the Ru‐catalyzed CH activations … Show more

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Cited by 2 publications
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“…Machine learning algorithms have been applied by researchers to automatically detect spam [15]. A bottleneck in developing such machine learning techniques is the lack of high quality labelled training data where human labelling to obtain high quality labelled data is expensive and not scalable [45]. Additionally, manually classifying spam can be time consuming.…”
Section: Resultsmentioning
confidence: 99%
“…Machine learning algorithms have been applied by researchers to automatically detect spam [15]. A bottleneck in developing such machine learning techniques is the lack of high quality labelled training data where human labelling to obtain high quality labelled data is expensive and not scalable [45]. Additionally, manually classifying spam can be time consuming.…”
Section: Resultsmentioning
confidence: 99%
“…4 Among them, there are extensive literature examples of redox-neutral strategies using rhodium and ruthenium catalysts. 5 But the 4d and 5d transition metals are not only costly due to their low abundance in nature but also generally toxic. As a result of this, the paradigm has shifted towards the use of cost-effective, more abundant, and less toxic 3d transition metals in the field of C–H functionalization.…”
Section: Introductionmentioning
confidence: 99%