Ru@C as a safety mask of RuO₄@C for selective catalytic oxidation of alkynyl sulfurs to prepare alkynylsulfones

Abstract

A high‐performance catalyst, RuO4@C, was safely generated in situ from a safety mask Ru@C, which was recyclable and commercially available. The catalyst could selectively oxidize thioethers to sulfones in 95%–99% yields and alkynyl sulfurs to alkynylsulfones in 93%–98% yields. This safe, non‐toxic, inexpensive, and readily available catalyst is potentially promising for industrial applications in the production of sulfones from sulfur oxidation.

Regulation of Photogenerated Redox Species through High Crystallinity Carbon Nitride for Improved C−S Coupling Reactions

“…Within the realm of medicinal chemistry and pharmaceutical research, sulfones, particularly the alkynyl variants, play a crucial role due to their noteworthy pharmacological properties (Scheme 1a) [1] and versatility as synthetic intermediates in a range of chemical reactions like cycloadditions, conjugated additions, and cross-coupling reactions. [2] Traditional synthetic methodologies for alkynyl sulfones, incorporating the oxidation of alkynyl sulfides, [3] sulfonylation of alkynylsilanes or alkynylstannides, [4] and dehydrohalogenation of vinyl sulfones, [5] necessitate pre-functionalized substrates or elaborate multistep procedures. The evolution of CÀ S coupling reactions [6] employing sulfonyl radicals offers a more efficient and direct strategy for the synthesis of alkynyl sulfones.…”