Abstract:Background
Anal abscess is an important complication of anal fissure (AF), whereas interleukin‐6R (IL‐6R) has been implicated in the development of abscess. In this study, we aimed to explore the possible molecular mechanisms underlying the regulatory effects of miRNAs on IL‐6R and other inflammatory factors related to the induction of anal abscess in AF.
Methods
Bioinformatics analysis, luciferase assay, real‐time polymerase chain reaction, and Western blot analysis were performed to identify the possible reg… Show more
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