“…Contrary to the action of many traditional NSAIDs, DIC inhibits cyclooxygenase (COX)-2 enzyme with greater potency than it does COX-1 [3,4] in vitro and in vivo, thus decreasing the production of prostaglandins, prostacyclines and thromboxanes. It is widely used in management of mild to moderate pain, when inflammatory is also present as in cases of rheumatoid arthritis, osteoarthritis [5], ankylosing spondylitis, gouty arthritis [6], tendinitis, and bursitis [7], and certain nonrheumatic conditions, and in other inflammatory painful conditions such as postoperative pain, treatment of dysmenorrhea, back pain, sciatica [8,9].…”