2012
DOI: 10.1016/j.soard.2011.09.022
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Roux-en-Y gastric bypass ameliorates polycystic ovary syndrome and dramatically improves conception rates: a 9-year analysis

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Cited by 100 publications
(73 citation statements)
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“…Weight loss following bariatric surgery leads to improved sex hormone profiles and improvement of metabolic and hormonal changes associated with polycystic ovarian syndrome (PCOS), thereby increasing fertility [92,93,94]. For instance, Legro et al [93] demonstrated follicular phase shortening, reduction in android fat and improved female sexual function in women post-RYGB.…”
Section: Pregnancy After Bariatric Surgerymentioning
confidence: 99%
See 1 more Smart Citation
“…Weight loss following bariatric surgery leads to improved sex hormone profiles and improvement of metabolic and hormonal changes associated with polycystic ovarian syndrome (PCOS), thereby increasing fertility [92,93,94]. For instance, Legro et al [93] demonstrated follicular phase shortening, reduction in android fat and improved female sexual function in women post-RYGB.…”
Section: Pregnancy After Bariatric Surgerymentioning
confidence: 99%
“…For instance, Legro et al [93] demonstrated follicular phase shortening, reduction in android fat and improved female sexual function in women post-RYGB. A study looking at PCOS following RYGB demonstrated improvements in hirsutism, type 2 diabetes mellitus and fertility [94]. Following bariatric surgery, fertility can rapidly improve, even in previously anovulatory women [95].…”
Section: Pregnancy After Bariatric Surgerymentioning
confidence: 99%
“…Of the 19 remaining studies, 5 were excluded due to inadequate outcome measures and 1 was excluded because the number of female study subjects was unknown. A total of 13 primary studies (10 full manuscripts and 3 abstract studies) consisting of no randomized controlled trials, 13 case-series [11][12][13][14][15][16][17][18][19][20][21][22][23], and no case reports were selected for review and meta-analysis ( Fig. 1).…”
Section: Resultsmentioning
confidence: 99%
“…Two additional studies published in the last years found that bariatric surgery may have an important albeit not universal benefit on hirsutism in massively obese women with PCOS. One study (96) found that in 20 women with severe obesity and PCOS, a Roux-en-Y gastric bypass significantly ameliorated menses and conception rates in most, and resolved hirsutism in 29% of them. A second study (97) reviewed the outcomes of 24 massively obese women diagnosed with PCOS who had undergone elective laparoscopic gastric bypass surgery and found that all but one were hirsute before surgery but 12 (52%) had complete resolution at a mean follow-up of 8G2.3 months, six (25%) had moderate resolution at a mean of 21G18 months, three had minimal resolution at 34G14 months and, finally, two women reported no change in their hirsutism at 32G7 months.…”
Section: Bariatric Surgerymentioning
confidence: 99%