Routine ultrasound for suspected appendicitis in children: a single-centre retrospective cohort study

Abstract

Introduction Appendicitis continues to be a common surgical emergency in children, but its diagnosis remains challenging. Use of diagnostic imaging to confirm appendicitis has gained popularity in some countries because it is associated with lower negative appendicectomy rates. This study reports our centre’s experience of adopting routine ultrasound for the investigation of suspected appendicitis in children. Methods A single-centre retrospective cohort study was performed investigating all children aged 5–16 years admitted under surgeons with suspected appendicitis, in January–December 2019. Primary outcomes were the rate of ultrasound use, its accuracy in diagnosing/excluding appendicitis and negative appendicectomy rate. Other outcomes were treatment received, length of stay and complications. Results The majority of the 193 children with suspected appendicitis underwent a diagnostic ultrasound (87.5%). Ultrasound was highly sensitive (0.90, 95% confidence interval (CI) 0.81–0.96) and specific (1.0, 95% CI 0.96–1.0) for appendicitis in this study. Negative appendicectomy rate was extremely low (1.4%). Laparoscopic appendicectomy was the preferred management (75/86), with one case started open and no conversions to open. A minority of cases of simple appendicitis (10/86) were treated primarily with antibiotics. Rates of complex appendicitis and postoperative complications were similar to other studies. Conclusion Ultrasound can be highly sensitive and specific for appendicitis. Its routine use to confirm appendicitis prior to surgery is associated with a low negative appendicectomy rate. This is a major change in practice for a general surgical unit in the United Kingdom.

Obesity Is Associated With Decreased Accuracy of Ultrasound for Diagnosing Appendicitis: A Prospective Pediatric Cohort

“…[2][3][4][5] Ultrasound (US) is currently recognized as the criterion standard for diagnosing AA in the pediatric population. 6,7 However, an inaccurate US result can lead to an unnecessary appendectomy or to appendicitis being missed. Although many studies have examined the effect of obesity on the accuracy of US, the results of these studies are conflicting.…”

NETworking for Health and in Disease: Neutrophil Extracellular Traps in Pediatric Surgical Care

“…However, the identification of patients with non-complicated AA is still challenging. As CT scans involve radiation and are generally avoided for pediatric diagnostics [ 74 ], the prediction of complicated AA typically relies on patient history, clinical findings, laboratory values such as WBC count, granulocyte count, CRP concentration, and ultrasound [ 75 , 76 ]. Many efforts have been made to find new biomarkers to help differentiate between complicated and uncomplicated appendicitis [ 77 ].…”