Routine Serologic Screening for Syphilis in Hospitalized Patients

Burton, Albert A.; Flynn, John A.; Neumann, Theresa; Wilson, Charlton; Quinn, Thomas C.; Hook, Edward W.

doi:10.1097/00007435-199405000-00002

Cited by 8 publications

(3 citation statements)

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“…The highest reported prevalence, 18%, was among hospitalized patients aged 50+ in Baltimore, MD between 1990–1991. 14 In a longitudinal study of heterosexual couples between 1993–2002, the syphilis case rate for both males and females was 0.1%. 13 Older blood donors had low rates, with 0.4% of first-time donors seropositive for syphilis and 0% for active infection.…”

Section: Resultsmentioning

confidence: 99%

“…37 Importantly, these figures represent frequency of infection among people with diagnosed HIV who are receiving care; STI rates may differ for individuals with undiagnosed HIV. Compounding the lack of available data on infection frequency and rates in this demographic, only one of the included articles In this review, several studies found higher prevalence of syphilis among older patients compared to younger counterparts, 12,14,18 In general, syphilis was more commonly diagnosed among men than women, 11 especially in widowed men. 13 Older participants were more likely than younger to have late-stage syphilis 20 and had significantly increased odds for untreated syphilis.…”

Section: Discussionmentioning

confidence: 99%

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The burden of chlamydia, gonorrhea, and syphilis in older adults in the United States: A systematic review

et al. 2023

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Background Increases in life expectancy, the availability of sexual performance enhancing medication, and changes in sexual partnering suggest that sexually transmitted infections (STIs) among older persons could be on the rise, yet there have been relatively few studies examining STIs in this demographic. Our systematic review aimed to further characterize the incidence and prevalence of chlamydia, gonorrhea, and syphilis, along with associated risk factors among older adults (45 years or older) in the United States. Methods We searched five electronic databases (PubMed, Embase, Cinahl, Web of Science, and Global Health) for data published from inception to January 2021. The retrieved articles were screened based on eligibility criteria, and subsequent review of relevant article bibliographies was conducted. Results Of 4748 articles identified, 23 studies met our inclusion criteria and one additional article was identified through bibliography review. Of the 23 included articles, only 3 (11.5%) were focused exclusively on evaluating STIs in an older population. We found prevalence to be the following ranges: syphilis (0–18%), chlamydia (0–14.2%) and gonorrhea (0–15%). Few studies specifically investigated risk factors in this demographic. Conclusions The understudied burden of STIs in the older adult population substantiates the need to recognize issues surrounding sexuality in this demographic.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The burden of chlamydia, gonorrhea, and syphilis in older adults in the United States: A systematic review

et al. 2023

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“…Tests like treponema pallidum haemagglutination (TPHA) or fluorescent treponemal antibody absorption test are recommended for confirmation. [12][13][14][15] …”

Section: Introductionmentioning

confidence: 99%