“…This may manifest clinically as blanched, mottled skin, peripheral cyanosis, weak pulses, and consequently, permanent tissue necrosis if urgent intervention is not instituted ( Sadat et al, 2015 , Arshad and McCarthy, 2009 ). The conventional management of peripheral ischemia caused by arterial lines consists of urgent catheter removal, elevation of the affected limb, and induction of reflex vasodilation by applying heat to the contralateral limb ( Dilli et al, 2015 , Arshad and McCarthy, 2009 ). In most cases, these combined strategies fall short of improvement and further measures need to be implemented.…”