Rothia spp. infective endocarditis: A systematic literature review

Franconieri, Frédéric; Join‐Lambert, Olivier; Créveuil, Christian; Auzou, Michel; Labombarda, Fabien; Aouba, Achille; Verdon, Renaud; Blanchardière, A. de La

doi:10.1016/j.medmal.2020.10.021

Cited by 20 publications

(28 citation statements)

References 145 publications

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“…Moreover, 87% of these significantly decreased with sampling height based on log‐twofold‐change differential analysis ( p ≤ 0.01). These taxa contain bacteria that have been associated with a number of diseases, including infective endocarditis ( Rothia mucilaginosa ) 34 and gut mucosal damage ( Prevotella copri ) 35 . More information on these diseases can be found in Supplementary Materials, Appendix D, Fig.…”

Section: Resultsmentioning

confidence: 99%

Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

Robinson

Cando‐Dumancela

Antwis

et al. 2021

Sci Rep

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Exposure to biodiverse aerobiomes supports human health, but it is unclear which ecological factors influence exposure. Few studies have investigated near-surface green space aerobiome dynamics, and no studies have reported aerobiome vertical stratification in different urban green spaces. We used columnar sampling and next generation sequencing of the bacterial 16S rRNA gene, combined with geospatial and network analyses to investigate urban green space aerobiome spatio-compositional dynamics. We show a strong effect of habitat on bacterial diversity and network complexity. We observed aerobiome vertical stratification and network complexity that was contingent on habitat type. Tree density, closer proximity, and canopy coverage associated with greater aerobiome alpha diversity. Grassland aerobiomes exhibited greater proportions of putative pathogens compared to scrub, and also stratified vertically. We provide novel insights into the urban ecosystem with potential importance for public health, whereby the possibility of differential aerobiome exposures appears to depend on habitat type and height in the airspace. This has important implications for managing urban landscapes for the regulation of aerobiome exposure.

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Section: Resultsmentioning

confidence: 99%

Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

Robinson

Cando‐Dumancela

Antwis

et al. 2021

Sci Rep

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“…A literature review was done in 2003 by Boudewijns et al It identified 20 cases of R. dentocariosa endocarditis [10]. In a recent literature review published in 2020 by Franconieri et al, which included 51 cases of rothia induced endocarditis, 55% of them were due to Rothia dentocariosa [11]. Of the cases of R. dentocariosa endocarditis, 64% had pre-existing valve disease, and 46% had Bucco dental diseases.…”

Section: Discussionmentioning

confidence: 99%

“…The organism is usually susceptible to penicillin and cephalosporins. Treatment is by beta-lactam antibiotics for 4–6 weeks; options include penicillin with or without gentamicin or ceftriaxone [ 11-12 ]. Our patient had mitral valve endocarditis, which was complicated by vertebral osteomyelitis and hemorrhagic embolic strokes believed to be septic emboli as a result of endocarditis.…”

Section: Discussionmentioning

confidence: 99%

A rare report of Rothia dentocariosa endocarditis

Elkattawy

Alyacoub

Younes

et al. 2021

Journal of Community Hospital Internal Medicine Perspectives

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Rothia species are gram positive, round to rod-shaped bacteria that are normally oral and respiratory tract flora. They were first isolated in 1967 from dental caries. We present a 69-year -old male with no risk factors for aforementioned bacteria however was found to have thickened anterior leaflet of the mitral valve with a small isoechoic lesion consistent with vegetation on Transthoracic echocardiogram. Blood cultures grew pan sensitive Rothia dentocariosa. Patient was treated with long-term antibiotics. This case adds to the limited number of cases of Rothia dentocariosa Endocarditis.

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“…It is a commensal of the human oropharynx, upper respiratory tract, and duodenum [ 29 , 30 ]. There are three human species: R. aeria , R. dentocariosa , and R. mucilaginosa , respectively isolated in 2003, 1949, and 1900 [ 31 , 32 , 33 ]. All three can cause disease in humans, mainly in the oral cavity, and also invasive infections, such as endocarditis [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

“…There are three human species: R. aeria , R. dentocariosa , and R. mucilaginosa , respectively isolated in 2003, 1949, and 1900 [ 31 , 32 , 33 ]. All three can cause disease in humans, mainly in the oral cavity, and also invasive infections, such as endocarditis [ 33 ]. Recently, Rothia spp has been linked with the emergence and persistence of gastric atrophy and intestinal metaplasia after Helicobacter pylori eradication [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Gut Microbiota in Military International Travelers with Doxycycline Malaria Prophylaxis: Towards the Risk of a Simpson Paradox in the Human Microbiome Field

et al. 2021

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Dysbiosis, developed upon antibiotic administration, results in loss of diversity and shifts in the abundance of gut microbes. Doxycycline is a tetracycline antibiotic widely used for malaria prophylaxis in travelers. We prospectively studied changes in the fecal microbiota of 15 French soldiers after a 4-month mission to Mali with doxycycline malaria prophylaxis, compared to changes in the microbiota of 28 soldiers deployed to Iraq and Lebanon without doxycycline. Stool samples were collected with clinical data before and after missions, and 16S rRNA sequenced on MiSeq targeting the V3-V4 region. Doxycycline exposure resulted in increased alpha-biodiversity and no significant beta-dissimilarities. It led to expansion in Bacteroides, with a reduction in Bifidobacterium and Lactobacillus, as in the group deployed without doxycycline. Doxycycline did not alter the community structure and was specifically associated with a reduction in Escherichia and expression of Rothia. Differences in the microbiota existed at baseline between military units but not within the studied groups. This group-effect highlighted the risk of a Simpson paradox in microbiome studies.

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Rothia spp. infective endocarditis: A systematic literature review

Cited by 20 publications

References 145 publications

Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

Exposure to airborne bacteria depends upon vertical stratification and vegetation complexity

A rare report of Rothia dentocariosa endocarditis

Gut Microbiota in Military International Travelers with Doxycycline Malaria Prophylaxis: Towards the Risk of a Simpson Paradox in the Human Microbiome Field

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