Rotavirus genotypes in Belarus, 2008–2012

Semeiko, Galina V.; Yermalovich, Marina A.; Poliakova, Nadezhda; Mijatovic-Rustempasic, Slavica; Kerin, Tara; Wasley, Annemarie; Videbaek, Dovile; Gentsch, Jon R.; Bowen, Michael D.; Самойлович, Е. О.

doi:10.1016/j.meegid.2014.09.007

Cited by 3 publications

(1 citation statement)

References 27 publications

(36 reference statements)

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“…In Republic of Korea, the most common genotypes were G1P(8), G2P(4) and G9P (8) in the study published by Kim et al [1], while Boula et al [15] reported G9P(8), G1P(8) and G3P(6) genotypes in Cameroon. In contrast, Semeiko et al [16] found the G4P(8) as the predominant genotype in Belarus.…”

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confidence: 85%

Prevalence and genotype distribution of rotaviruses in children with gastroenteritis in Rize province

et al. 2015

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Determination of the distribution of rotavirus genotypes is essential for understanding the epidemiology of this virus responsible for nearly half a million of deaths in patients with gastroenteritis worldwide. In the present study, we aimed to genotype the rotavirus strains isolated from diarrheal stool samples in children under 5 years old. A total of 1297 fecal samples were collected, and rotavirus antigen was detected in 73 of these samples. Antigen-positive samples were transferred to the Public Health Agency of Turkey, Molecular Microbiology Research Laboratory, and were tested for determination of genotypes G and P using semi-nested multiplex polymerase chain reaction method performed with consensus- and genotype-specific primers. Twelve specimens were found to be negative for rotavirus in genotyping method. All the positive-strains were in G1-4, G8-9, P(4), P(8), and P(9) genotypes. The most frequent GP genotype combinations were found to be G9P(8) in 21 strains (34.4%), G2P(4) in 14 strains (23.0%), and G1P(8) in 12 strains (19.7%). We found 10 distinct genotypes amongst a total of 61 strains. Among the strains isolated and genotyped in our study, 90.2% (55/61) and 67.2% (41/61) have already been included in the two existing commercial vaccines. In conclusion, these findings implicate the necessity of development of region-specific vaccines after evaluation of the local genotype distribution. Further studies on the large number of rotavirus strains would contribute to this process.

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