Rotational micro‐CT using a clinical C‐arm angiography gantry

Patel, Vikas; Hoffmann, Kenneth R.; Ionita, Ciprian N.; Keleshis, Christos; Bednarek, Daniel R.; Rudin, Stephen

doi:10.1118/1.2989989

Cited by 15 publications

(16 citation statements)

References 24 publications

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“…We investigated the feasibility of using the high resolution and high exposure VOI projection data in conjunction with limited height, full width projection data acquired at low resolution, and low exposure to reconstruct high resolution CBCT images for the VOI. Patel et al 28 used similar approach to implement their ROI cone beam CT technique for neuroangiography.…”

Section: Introductionmentioning

confidence: 99%

Dual resolution cone beam breast CT: A feasibility study

et al. 2009

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Purpose: In this study, the authors investigated the feasibility of a dual resolution volume-ofinterest ͑VOI͒ cone beam breast CT technique and compared two implementation approaches in terms of dose saving and scatter reduction. Methods: With this technique, a lead VOI mask with an opening is inserted between the x-ray source and the breast to deliver x-ray exposure to the VOI while blocking x rays outside the VOI. A CCD detector is used to collect the high resolution projection data of the VOI. Low resolution cone beam CT ͑CBCT͒ images of the entire breast, acquired with a flat panel ͑FP͒ detector, were used to calculate the projection data outside the VOI with the ray-tracing reprojection method. The Feldkamp-Davis-Kress filtered backprojection algorithm was used to reconstruct the dual resolution 3D images. Breast phantoms with 180 m and smaller microcalcifications ͑MCs͒ were imaged with both FP and FP-CCD dual resolution CBCT systems, respectively. Two approaches of implementing the dual resolution technique, breast-centered approach and VOI-centered approach, were investigated and evaluated for dose saving and scatter reduction with Monte Carlo simulation using a GEANT4 package. Results:The results showed that the breast-centered approach saved more breast absorbed dose than did VOI-centered approach with similar scatter reduction. The MCs in fatty breast phantom, which were invisible with FP CBCT scan, became visible with the FP-CCD dual resolution CBCT scan. Conclusions:These results indicate potential improvement of the image quality inside the VOI with reduced breast dose both inside and outside the VOI.

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Section: Introductionmentioning

confidence: 99%

Dual resolution cone beam breast CT: A feasibility study

et al. 2009

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“…They have more pronounced effects for general applications with less image contrast 34 or small structures such as stent struts ͑e.g., 0.1 mm or lower͒ 35,37 using a microangiographic fluoroscopic imaging system. 37,38 In our case, the studied objects such as selective CA enhanced vascular structures are imaged with high dose and are highly contrasted. Also, the object size is expected to be in a larger magnitude.…”

Section: Discussionmentioning

confidence: 98%

Dynamic estimation of three‐dimensional cerebrovascular deformation from rotational angiography

et al. 2011

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181 Purpose: The objective of this study is to investigate the feasibility of detecting and quantifying 3D cerebrovascular wall motion from a single 3D rotational X-ray angiography (3DRA) acquisition within a clinically acceptable time, and computing from the estimated motion field for the further biomechanical modeling of the cerebrovascular wall. Methods:The whole motion cycle of the cerebral vasculature is modeled using a 4D B -spline transformation, which is estimated from a 4D to 2D+t image registration framework. The registration is performed by optimizing a single similarity metric between the entire 2D+t measured projection sequence and the corresponding forward projections of the deformed volume at their exact time instants. The joint use of two acceleration strategies together with their implementation on graphics processing units are also proposed so as to reach computation times close to clinical requirements. For further characterizing vessel wall properties, an approximation of the wall thickness changes is obtained through a strain calculation.Results: Evaluation on in silico and in vitro pulsating phantom aneurysms demonstrated an accurate estimation of wall motion curves. In general, the error was below 10% of the maximum pulsation, even in the situation when substantial inhomogeneous intensity pattern was present. Experiments on in vivo data provided realistic aneurysm and vessel wall motion estimates, whereas in regions where motion was neither visible nor anatomically possible no motion was detected. The use of the acceleration strategies enabled completing the estimation process for one entire cycle in 5-10 minutes without degrading the overall performance. The strain map extracted from our motion estimation provided a realistic deformation measure of the vessel wall. Conclusions:Our technique has demonstrated that it can provide accurate and robust 4D estimates of cerebrovascular wall motion within a clinically acceptable time, although it has to be applied to a larger patient population prior to possible wide application to routine endovascular procedures. In particular, 2 for the first time, this feasibility study has shown that in vivo cerebrovascular motion can be obtained intra-procedurally from a 3DRA acquisition. Results have also shown the potential of performing strain analysis using this imaging modality, making thus possible for the future modeling of biomechanical properties of the vascular wall.

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“…However, the sparse overview scans add dose and time and impose registration constraints between the overview and the VOI scan. Patel et al 22 explored a similar technique by mounting a microangiographic fluoroscope onto the regular angiography equipment to preserve the small details required for neuroradiologic applications. Similar techniques that use dual detectors have been proposed for breast imaging applications that can be extended to neuroradiology applications.…”

Section: Figmentioning

confidence: 99%

The Added Value of Volume-of-Interest C-Arm CT Imaging during Endovascular Treatment of Intracranial Aneurysms

Chintalapani

Chinnadurai

Maier

et al. 2015

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:Successful endovascular treatment of intracranial aneurysms requires understanding the exact relationship of implanted devices to the aneurysm, parent artery, and other branch vessels during the treatment. Intraprocedural C-arm CT imaging has been shown to provide such information. However, its repeated use is limited due to increasing radiation exposure to the patient. The goal of this study was to evaluate a new volume-of-interest C-arm CT imaging technique, which would provide device-specific information through multiple 3D acquisitions of only the region of interest, thus reducing cumulative radiation exposure to the patient.

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Rotational micro‐CT using a clinical C‐arm angiography gantry

Cited by 15 publications

References 24 publications

Dual resolution cone beam breast CT: A feasibility study

Dual resolution cone beam breast CT: A feasibility study

Dynamic estimation of three‐dimensional cerebrovascular deformation from rotational angiography

The Added Value of Volume-of-Interest C-Arm CT Imaging during Endovascular Treatment of Intracranial Aneurysms

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