Rosin: Recent advances and potential applications in novel drug delivery system

Abstract

Gum exudates are among the oldest natural polymer. Natural gums have remained one of the major areas of interest for the researchers for their applicability in the drug delivery system because of their wide availability, inexpensiveness and availability in a variety of structures with varied properties. They can be easily modified chemically, biochemically and are highly stable, safe, non-toxic, gel forming and in addition are biodegradable. Rosin is one of the natural gums obtained as resinous constituent of the oleoresin exuded by various species of pine, mostly conifers. Rosin consists primarily of abietic- and pimaric-type resin acids (or rosin acids) with characteristic hydrophobic hydrophenanthrene rings which impart them excellent film-forming properties. Rosin and its derivatives are biopolymers that are increasingly used for their pharmaceutical applications. In the pharmaceutical field, it has been investigated for film-forming and coating properties, microencapsulation and as a matrix material in the tablets for sustained and controlled drug release. This article reviews the literature on rosin and its derivative and describes the varied applications of the rosin and their future exploitation in novel drug delivery systems.

A Deeper Microscopic Study of the Interaction between Gum Rosin Derivatives and a Mater-Bi Type Bioplastic

“…The esters were: (i) Unik Tack P100 resin kindly supplied by United Resins (Figueira da Foz, Portugal), with a softening point of 90 • C, an acid number of 15 and Gardner color of 4 (labeled as UT); and (ii) Lurefor 125 resin kindly supplied by LureSA (Segovia, Spain), with a softening point of 125 • C, an acid number of 11.9 and Gardner color of 7 (labeled as LF). As described, LF and UT differ from each other in the acid number, which denotes that the number of functionalized groups in the modified structure is greater in LF than in UT [27][28][29].…”

New Materials for 3D-Printing Based on Polycaprolactone with Gum Rosin and Beeswax as Additives

“…The structure of GR can be modified given its acidity and hydrophobicity [20][21][22][23]. GR has a glassy, translucent, and bright appearance, and a yellowish coloration [24,25]. Its melting temperature is around 75 • C [24,26].…”

Yttrium fumaropimarat as a novel heat stabilizer for poly(vinyl chloride)

“…Moreover, rosin was a kind of renewable resource, which was widely used in many fields due to its molecular characterization. Fumaropimaric acid was a deep processing compound of rosin, which contained a double bond and three carboxyl groups. In this article, the three carboxyl groups were used for the reaction with yttrium acetate.…”