Rosa davurica Pall., Rosa rugosa Thumb., and Rosa acicularis Lindl. Originating from Far Eastern Russia: Screening of 146 Chemical Constituents in Three Species of the Genus Rosa

Razgonova, Mayya P.; Баженова, Б. А.; Zabalueva, Yulia Yu.; Burkhanova, Anastasia G.; Zakharenko, Alexander M.; Kupriyanov, A. N.; Sabitov, Andrey; Erċışlı, Sezai; Golokhvast, Kirill S.

doi:10.3390/app12199401

Cited by 16 publications

(3 citation statements)

References 109 publications

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“…The fragment ion with m/z 146.19 yields two daughter ions at m/z 144.19 and m/z 118.23. It has been identified in the bibliography in extracts from Huolisu Oral Liquid [7], Rosa acicularis [8], Camellia kucha [9], Euphorbia hirta [10], Hylocereus polyrhizus [11], and rapeseed flower petals [12]. The CIDspectrum in positive ion modes of atractylenolide II from extracts of A. martjanovii from the Botanical Garden of NEFU are shown in Figure 4.…”

Section: Resultsmentioning

confidence: 99%

Primary Determination of the Composition of Secondary Metabolites in the Wild and Introduced Artemisia martjanovii Krasch: Samples from Yakutia

Okhlopkova,

Ercisli,

Razgonova

et al. 2023

Horticulturae

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Artemisia martjanovii Krasch is a rare representative of the genus Artemisia in Siberia and the Far East. The phytochemical composition of this endangered species is essential for its potential use in medicine. We used tandem mass spectrometry and HPLC-MS/MS methods to describe the metabolome from the stem and leaf extracts of A. martjanovii from Yakutia. The metabolome profile analysis of A. martjanovii grown in the Botanical Garden of the North-Eastern Federal University, Yakutsk, Russia, and the wild A. martjanovii from Khangalassky district, Republic of Sakha (Yakutia) differed significantly both in the polyphenol composition and other compound classes. In total, we identified 104 bioactive constituents from stem and leaf extracts, 56 compounds from the polyphenol group, and 48 from other compound classes. Twenty-seven compounds classified as polyphenol groups, i.e., flavones apigenin, trihydroxy(iso)flavone, salvigenin, cirsiliol, cirsilineol, nevadensin, syringetin, gardenin B, thymonin, and chrysoeriol C-hexoside; flavonols: taxifolin, tetrahydroxy-dimethoxyflavone-hexoside, etc.; and 26 compounds from other classes are being reported for the first time in the genus Artemisia L.

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Section: Resultsmentioning

confidence: 99%

Primary Determination of the Composition of Secondary Metabolites in the Wild and Introduced Artemisia martjanovii Krasch: Samples from Yakutia

Okhlopkova,

Ercisli,

Razgonova

et al. 2023

Horticulturae

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“…is well known in northeastern Asia as a food source enriched with vitamins C and E [ 13 ]. Various therapeutical effects of R. davurica have been identified, such as antioxidant, anti-HIV, antiviral, antibiotics, and hypoglycemic activities [ 14 ]. Our previous study demonstrated the antioxidative and photoprotective effects of R. davurica leaf extract on in vitro human keratinocytes models [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Rosa davurica Inhibited Allergic Mediators by Regulating Calcium and Histamine Signaling Pathways

Lim

Oh²,

Nguyen

et al. 2023

Plants

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Rosa davurica Pall. exhibits antioxidant, antiviral, and anti-inflammatory properties; however, its pharmacological mechanism in allergy is yet to be understood. This study confirmed the effects of R. davurica Pall. leaf extract (RLE) on allergy as a new promising material. To evaluate the therapeutic potential of RLE against allergy, we investigated the effects of RLE on the regulatory β-hexosaminidase, histamine, histidine decarboxylase (HDC), Ca2+ influx, nitric oxide (NO), and cytokines induced by lipopolysaccharide (LPS) and DNP-IgE/BSA in Raw 264.7 and RBL-2H3 cells. Furthermore, we examined the effects of RLE on the signaling pathways of mitogen-activated protein kinase (MAPK) and Ca2+ pathways. After stimulating Raw 264.7 cells with LPS, RLE reduced the release of inflammatory mediators, such as NO, cyclooxygenase (COX)-2, inducible nitric oxygen synthase (iNOS), interleukin (IL)-1β, -6, and tumor necrosis factor (TNF)-α. Also, RLE reduced the β-hexosaminidase, histamine, HDC, Ca2+ influx, Ca2+ pathways, and phosphorylation of MAPK in DNP-IgE/BSA-stimulated RBL-2H3 cells. Our studies indicated that RLE is a valuable ingredient for treating allergic diseases by regulating cytokine release from macrophages and mast cell degranulation. Consequently, these results suggested that RLE may serve as a possible alternative promising material for treating allergies.

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“…Furthermore, the plant's flowers contribute to the formulation of perfumes and cosmetic products. Notably, the leaves and fruits of R. davurica boast a richness in ascorbic acid, commonly recognized as vitamin C, endowing them with notable properties, such as antioxidant, anticancer, and anti-aging effects [7,8]. A recent study revealed that a 30% ethanol extract from R. davurica inhibited UVB-induced photoaging [9].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity According to the Planting Interval and Collecting Time of Rosa davurica

Zheng,

Kim,

2023

Applied Sciences

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This study aimed to assess functional substances and antioxidant effects with respect to planting intervals and collection timing, with the goal of developing efficient planting methods for the mass harvesting of Rosa davurica and enhancing the availability of the plant’s edible parts in Korea. High-Performance Liquid Chromatography (HPLC) was employed to analyze the ethyl gallate content, a recognized functional component present in R. davurica, while the antioxidant effect was verified using DPPH, ABTS, and SOD assays. The findings revealed an increased yield of buds and leaves in R. davurica when the planting interval was reduced to 120 × 50 cm compared to the conventional 120 × 100 cm spacing. Specifically, the content of ethyl gallate remained consistent across different collection periods, and this result was associated with the varying planting intervals. While there were no significant changes in total polyphenol and flavonoid content, the collection from September demonstrated higher levels. Furthermore, the study established that leaf antioxidant activity, determined through IC50 values of DPPH and ABTS, surpassed that of the buds, with no significant difference in SOD activity being observed. Overall, no substantial differences were observed in the content of functional components between the buds and leaves of R. davurica, regardless of planting interval and collection timing. These results contribute valuable insights for optimizing planting methods for the large-scale collection of R. davurica leaves.

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Rosa davurica Pall., Rosa rugosa Thumb., and Rosa acicularis Lindl. Originating from Far Eastern Russia: Screening of 146 Chemical Constituents in Three Species of the Genus Rosa

Cited by 16 publications

References 109 publications

Primary Determination of the Composition of Secondary Metabolites in the Wild and Introduced Artemisia martjanovii Krasch: Samples from Yakutia

Primary Determination of the Composition of Secondary Metabolites in the Wild and Introduced Artemisia martjanovii Krasch: Samples from Yakutia

Rosa davurica Inhibited Allergic Mediators by Regulating Calcium and Histamine Signaling Pathways

Antioxidant Activity According to the Planting Interval and Collecting Time of Rosa davurica

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