ROS Responsive Silica Nanoparticles for Controlled and Targeted Drug Delivery

Prajapati, Dipak; Patani, Anil; Jain, Tanvi; Patel, Ashish; Singh, Sachidanand

doi:10.1007/978-981-99-1718-1_17

Cited by 2 publications

(2 citation statements)

References 71 publications

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“…As a member of the reductase oxidase family, CAT is known for its role in the prevention of ROS in general and by inhibiting ROS reactivity, it functions as an endogenous antioxidant and confers cellular protection against oxidative stress ( Kleniewska and Pawliczak, 2019 ). The metalloenzyme, SOD, facilitates the process of dismutation, wherein superoxide radicals (O 2 − ) undergo transformation into conventional oxygen (O 2 ) and hydrogen peroxide (H 2 O 2 ) molecules ( Lin et al, 2020 ; Prajapati et al, 2023 ). By virtue of its antioxidative properties, SOD serves as a protective agent against the harmful effects of oxidative stress on various tissues ( Sahoo and Chainy, 2007 ) and also represents a variant of the postbiotic entity that exhibits potential utility as an antioxidant moiety ( Hassaan et al, 2021 ).…”

Section: Mechanisms Of Actionmentioning

confidence: 99%

Postbiotic production: harnessing the power of microbial metabolites for health applications

Prajapati,

Patel,

Singh

et al. 2023

Front. Microbiol.

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Postbiotics, which are bioactive substances derived from the metabolic processes of beneficial microbes, have received considerable attention in the field of microbiome science in recent years, presenting a promising path for exploration and innovation. This comprehensive analysis looks into the multidimensional terrain of postbiotic production, including an extensive examination of diverse postbiotic classes, revealing their sophisticated mechanisms of action and highlighting future applications that might significantly affect human health. The authors thoroughly investigate the various mechanisms that support postbiotic production, ranging from conventional fermentation procedures to cutting-edge enzyme conversion and synthetic biology approaches. The review, as an acknowledgment of the field’s developing nature, not only highlights current achievements but also navigates through the problems inherent in postbiotic production. In order to successfully include postbiotics in therapeutic interventions and the production of functional food ingredients, emphasis is given to critical elements, including improving yields, bolstering stability, and assuring safety. The knowledge presented herein sheds light on the expanding field of postbiotics and their potential to revolutionize the development of novel therapeutics and functional food ingredients.

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Section: Mechanisms Of Actionmentioning

confidence: 99%

Postbiotic production: harnessing the power of microbial metabolites for health applications

Prajapati,

Patel,

Singh

et al. 2023

Front. Microbiol.

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“…Oxidative stress occurs when prooxidant molecules like ROS and reactive nitrogen species (RNS) get produced in excess when antioxidant systems are not working efficiently ( 34 , 35 ). The mitochondrial respiratory chain produces superoxide anion, hydroxyl radical, and hydrogen peroxide during aerobic metabolism ( 36 ).…”

Section: Oxidative Stressesmentioning

confidence: 99%

Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress

Patani,

Balram,

Yadav

et al. 2023

Front. Endocrinol.

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Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern in human health. The present review comprehensively examines various categories of endocrine dysregulation within the adrenal glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, a comprehensive account of adrenal hormone disorders, including adrenal insufficiency, Cushing’s syndrome, and adrenal tumors, is presented, with particular emphasis on their intricate association with oxidative stress. The review also delves into an examination of various nutritional antioxidants, namely vitamin C, vitamin E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, and probiotics, and elucidates their role in mitigating the adverse effects of oxidative stress arising from imbalances in adrenal hormone levels. In conclusion, harnessing the power of nutritional antioxidants has the potential to help with oxidative stress caused by an imbalance in adrenal hormones. This could lead to new research and therapeutic interventions.

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ROS Responsive Silica Nanoparticles for Controlled and Targeted Drug Delivery

Cited by 2 publications

References 71 publications

Postbiotic production: harnessing the power of microbial metabolites for health applications

Postbiotic production: harnessing the power of microbial metabolites for health applications

Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress

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