ROS-induced lipid transformations without oxygen participation

Elderberry (Sambucus nigra L.) juice as a novel functional product rich in health-promoting compounds

“…Reactive nitrogen species (RNS), as endogenous intermediates that continuously occur in living cells, play an essential role in the regulation of physiological processes, which is why different biological activities of cNO are conditioned by its radical character. 41 The elderberry juice also achieved strong total antioxidant and metal chelating potential. Signicant radical scavenging and a reducing power capability of elderberry juice were reached, and the obtained values ranged from 2.16-5.38 to 7.26-10.98 g TE per L juice.…”

“…Namely, as we determined, the examined juice is a good source of phenolics, and the ability to chelate metal ions shown by phenolic compounds is a function of their characteristic chemical structure, number, and position of hydroxyl groups. 41 It is important to point out that within this research, the ability of elderberry juice to inhibit lipid peroxidation, i.e. to prevent damage to cell membranes caused by free radicals, was also examined.…”

Characteristics of a novel photoinitiator aceanthrenequinone-initiated polymerization and cytocompatibility of its triggered polymer

“…The data have shown that monomers and photoinitiators cause cellular redox imbalance, which leads to apoptosis and DNA damage by increasing ROS levels [ 20 , 21 ]. Oxidative stress is involved in enhancement of intracellular ROS, resulting in damage to lipids, proteins and DNA, and is associated with numerous diseases [ [22] , [23] , [24] ]. CQ can trigger a rapid increase in intracellular ROS, which may eventually lead to mutagenesis [ 25 ].…”

Synthesis and activity of a coumarin‐based fluorescent probe for hydroxyl radical detection

“…The hydroxyl radical (ÁOH) is the most representative free radical in the human body, [1,2] and it is closely related to the occurrence and development of various diseases because of its strong oxidation ability, high reaction activity, and short half-time. [3][4][5][6][7][8] For example, ÁOH can induce a series of free radical reactions, causing lipid peroxidation of membrane unsaturated fatty acids, resulting in the local destruction and even dissolution of lipid membranes. [9][10][11][12] ÁOH can also change the activity of phosphoric acid and induce the release of arachidonic acid (AA) from membrane phospholipids.…”