This study sought to determine the influence of organizational factors on strategic change implementation in the County Government of Kakamega. The specific objective was to assess the influence of organizational communication on strategic change implementation in the County Government of Kakamega. This study was anchored to The Burke-Litwin Model of Organizational Change and Institutional Theory. The study adopted a descriptive survey research design. The target population of the study was 548 top level and middle level managers. Sampling frame consisted of Agriculture, Public Service, Social Services, Education, Health Services, ICT, Lands & Housing, Trade & Industrialization, Roads, Public Works & Energy, Finance and Economic Planning.Purposive and stratified sampling techniques were chosen and used to select the sample population of 232 respondents according to Yamane recommendation. Structured questionnaire were pre tested for validity and reliability was the main primary data collection tool. The primary data was analyzed using both descriptive and inferential statistics with SPSS as the analysis tool. The correlation findings indicated that there existed a significant relationship between organizational communication and strategic change implementation (P=0.582, P=0.000). Simple linear regression analysis revealed that organizational communication accounted up to 33.9% variation in strategic change implementation (R 2 =0.339). This implied that enhancement of transformational leadership will result to significant increase in strategic change implementation. The study concluded that organizational communication influenced strategic change implementation in the County Government of Kakamega. The study recommended that management should ensure employees are aware of the need for strategic change through proper communication channels using various mode and channel of communication. This would ensure that all communications from the management on strategic change management are delivered effectively to all employees.