Rolling “wool-balls”: rapid live-cell mapping of membrane sialic acids via poly-p-benzoquinone/ethylenediamine nanoclusters

Abstract

In this work, we design sticky, furry and fluorescent “wool-balls” based on p-benzoquinone/ethylenediamine polymer nanoclusters, which provide a convenient, fast labeling strategy for the imaging of cell surface sialic acids.

Customized Carbon Dots with Predictable Optical Properties Synthesized at Room Temperature Guided by Machine Learning

“…In contrast, the bottom-up approach uses small carbon molecules as precursors to grow into larger carbon structures, and a series of methods have been reported, such as ultrasound synthesis, microwave-assisted synthesis, room temperature route, hydrothermal route, chemical oxidation, etc . Among the above methods, the room temperature route is especially favorable, as it does not need severe synthesis conditions or elaborate equipment, which is green and sustainable. − For example, Chen et al prepared a series of fluorescent CDs at room temperature, and these CDs have been successfully applied for live-cell imaging and fluorescence detection. − Nevertheless, it is still challenging for researchers to obtain CDs suitable for biosensing with the desired properties (such as a specific emission wavelength) without performing a large-amount synthesis and screening. To avoid annoying repetitive work, it is necessary to develop a facile and highly predictable strategy to obtain CDs with favorable optical properties.…”

Large-Scale Manual Grinding Preparation of Ultrathin Porous Sulfur (S8)-Anchored ScOOH Nanosheets for Photothermal Conversion and Dye Adsorption

“…Advanced functional materials play an important role in promoting the progress and development of science and technology. − Among various functional materials, two-dimensional (2D) nanomaterials such as graphene and graphitic carbon nitride show high mechanical flexibility, optical transparency, and electronic properties because of the structural characteristics of ultrathin thickness, large lateral size, and surface area. − To improve the structural and functional properties of 2D nanomaterials, various strategies such as hybridization, , heteroatom doping, surface defect, and pore engineering have been developed. Of which, pore engineering endows 2D nanomaterials with nanopore structure to improve the density of active sites and the charge/mass transport, expanding their application ranges.…”

Recent advancements in the applications of carbon nanodots: exploring the rising star of nanotechnology

“…The experiments have been conducted using the developments of fluorescent carbon dots obtained from one-pot hydrothermal treatment of o -, m -, or p -phenylenediamines with triethylenetetramine. In vivo studies on zebrafish revealed the efficient and rapid excretion from the larval body within 48 h. This study assists in understanding RNA dynamics and basic biological processes, disease development, and drug interactions by Chen, et al 43 …”