Aluminum foam sandwiches (AFS) with AlSi10 foam cores and AISI 316L steel skins are manufactured by an in-situ bonding process. The precursor of the core foam was made with the powder compacted method. The precursor and skins, coupled together, were then heated up to the melting point of the Al alloy. The gas released by the blowing agent formed hydrogen bubbles in the melt. producing the foam. Such a porous structure was kept frozen at room temperature via cooling in cold water. To optimize the process conditions, some foaming experiments have been conducted with different holding times and temperatures. Such manufactured AFS were cut, chemically etched and studied with an optical microscope associated with image analysis software to get information about pores morphology in terms of circularity and equivalent diameter. The interface AlSi10-AISI316L has been characterized by SEM and EDX to investigate the bonding conditions between cores and skins. Finally, the AFS have been polished and etched to analyze the microstructure. Quasi-static compressive tests have been performed on the AFS. Obtained results showed that the interface formed during the foaming can be characterized by the inter-diffusion of alloying elements, as confirmed by the good quality of metallurgical joints.