Roles of TRPM7 in ovarian cancer

Wang, Zhi-Bin; Zhang, Xiu; Xiao, Fen; Liu, Zhao-Qian; Liao, Qian-Jin; Wu, Nayiyuan; Wang, Jing

doi:10.1016/j.bcp.2023.115857

Cited by 2 publications

(1 citation statement)

References 90 publications

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“…For instance, in case of breast cancer, the expression The role of TRPM7 has been repeatedly demonstrated in the regulation of Ca 2+ and Mg 2+ homeostasis, cell differentiation, cell viability, cell death and migration [33,[40][41][42][43][44][45]. Besides the central role of TRPM7 in physiological functions, it is also linked to pathological processes such as oncogenesis, cancer progression, tumor cell survival and metastasis [6,27,33,[46][47][48][49][50][51].…”

Section: Role Of Trpm Channels In Cancermentioning

confidence: 99%

The Role of TRPM7 in Oncogenesis

Köles,

Ribiczey,

Szebeni

et al. 2024

IJMS

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This review summarizes the current understanding of the role of transient receptor potential melastatin-subfamily member 7 (TRPM7) channels in the pathophysiology of neoplastic diseases. The TRPM family represents the largest and most diverse group in the TRP superfamily. Its subtypes are expressed in virtually all human organs playing a central role in (patho)physiological events. The TRPM7 protein (along with TRPM2 and TRPM6) is unique in that it has kinase activity in addition to the channel function. Numerous studies demonstrate the role of TRPM7 chanzyme in tumorigenesis and in other tumor hallmarks such as proliferation, migration, invasion and metastasis. Here we provide an up-to-date overview about the possible role of TRMP7 in a broad range of malignancies such as tumors of the nervous system, head and neck cancers, malignant neoplasms of the upper gastrointestinal tract, colorectal carcinoma, lung cancer, neoplasms of the urinary system, breast cancer, malignant tumors of the female reproductive organs, prostate cancer and other neoplastic pathologies. Experimental data show that the increased expression and/or function of TRPM7 are observed in most malignant tumor types. Thus, TRPM7 chanzyme may be a promising target in tumor therapy.

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Section: Role Of Trpm Channels In Cancermentioning

confidence: 99%

The Role of TRPM7 in Oncogenesis

Köles,

Ribiczey,

Szebeni

et al. 2024

IJMS

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Spicing Up Meat Preservation: Cinnamomum zeylanicum Essential Oil in Meat-Based Functional Foods—A Five-Year Review

Gheorghe-Irimia,

Tăpăloagă,

Tăpăloagă

et al. 2024

Foods

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Today, in the modern consumer era, we are facing a significant change in terms of preferences and behaviour. This tendency is not only a basic desire, but rather a significant social and cultural movement that exerts a tremendous influence on the food industry and correlated sectors. In this direction, food authorities and experts have thoroughly evaluated the practicality of employing natural preservation methods to enhance the quality and safety of foodstuffs, while preserving their nutritional and sensory attributes. Given this context, the development of meat products enhanced with Cinnamomum zeylanicum essential oil (CZEO) poses promising avenues, such as extended shelf-life due to its antimicrobial, antifungal, and antioxidant properties. CZEO also has many health benefits, rendering it as a promising ingredient in functional meat product formulations. Conversely, challenges such as higher associated costs, sensory interactions, and variability arise. Hence, the aim of this review is to offer a novel critical perspective on CZEO’s potential application as a functional ingredient in meat products formulations and to address the inherent associated challenges, based on the last five years of scholarly publications.

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Roles of TRPM7 in ovarian cancer

Cited by 2 publications

References 90 publications

The Role of TRPM7 in Oncogenesis

The Role of TRPM7 in Oncogenesis

Spicing Up Meat Preservation: Cinnamomum zeylanicum Essential Oil in Meat-Based Functional Foods—A Five-Year Review

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