Roles of LncRNAs in the Pathogenesis of Pulmonary Hypertension
Ting Liu,
Shuanglan Xu,
Jiao Yang
et al.
Abstract:Pulmonary hypertension (PH) is a persistently progressive, incurable,
multifactorial associated fatal pulmonary vascular disease characterized by
pulmonary vascular remodeling. Long noncoding RNAs (lncRNAs) are involved in
regulating pathological processes such as pulmonary vasoconstriction, thickening,
remodeling, and inflammatory cell infiltration in PH by acting on different cell
types. Because of their differential expression in PH patients, as demonstrated
by the observation that some lncRNAs are si… Show more
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