Roles of Bothrops jararacussu toxins I and II: Antiviral findings against Zika virus

Effect of proteins isolated from Brazilian snakes on enterovirus A71 replication cycle: An approach against hand, foot and mouth disease

“…Proteins isolated from animal venoms have shown to be a fruitful source of molecules with several biological activities, such as anti-inflammatory, anti-cancer, and cardiovascular activity [ 28 – 30 ]. Among those, proteins isolated from Brazilian snake venoms, such as Bothrops moojeni and Crotalus durissus terrificus [ 31 ] have shown antiviral activity against hepatitis C virus (HCV) [ 32 ], dengue virus (DENV) and yellow fever virus (YFV) [ 33 ], measles virus [ 34 ], Chikungunya virus (CHIKV) [ 35 ], and ZIKV [ 36 ]. Therefore, the biological properties presented by the constituents of snake venoms represent promising sources for the identification and development of drugs against emergent viruses.…”