Role of Ultrasonography in Knee Osteoarthritis

Oo, Win Min; Bo, Myat Thae

doi:10.1097/rhu.0000000000000436

Cited by 43 publications

(46 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since Keen et al reported its clinimetrics, mainly with a focus on validity, in a systematic review in 2009, based on PubMed and Medline database searches 20 , many ultrasound OA studies have been published according to recent narrative reviews 21,22 , with most papers having sound methodology, utilizing more advanced technology such as high-frequency probes, and use of definitions and techniques from OMERACT 23 and European League Against Rheumatism (EULAR) Ultrasound Working Groups 24 . The increase in knowledge base in this area, therefore, warrants an update of the previous review in terms of clinimetrics (clinical measurement) such as reliability, validity, responsiveness 25 .…”

Section: Introductionmentioning

confidence: 99%

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis

Linklater²,

Daniel

et al. 2018

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis

Linklater²,

Daniel

et al. 2018

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

show abstract

“…Musculoskeletal US is an established technique for assessing the progression of knee joint OA and can be used as an imaging biomarker [33].…”

Section: Discussionmentioning

confidence: 99%

Correlation between protein YKL-40 and ultrasonographic findings in active knee osteoarthritis

et al. 2018

View full text Add to dashboard Cite

The aim of our study was to analyze the level of the glycoprotein YKL-40 in patients with active knee osteoarthritis (OA) and to search possible correlations with local inflammation and ultrasound (US) findings.Material and methods: A prospective study with fifty consecutive patients with active knee OA (diagnosed based on the American College of Rheumatology criteria for OA with radiographic confirmation) was performed. Concentrations of YKL-40 in serum and synovial fluid were measured by ELISA. US examinations – Gray scale (GS) US and Power Doppler (PD) US – of the knee was performed according to international guidelines. The suprapatellar, medial and lateral parapatellar recesses were scanned in each knee to evaluate synovial hypertrophy and vascularization.Results: Forty women (mean age 61.50±11.33 years old) and 10 men (aged 68.50±6.60 years old) were enrolled. We found that the synovial level of the glycoprotein (237.80±104.08 ng/ml) was significantly higher compared to the serum concentration (112.83±60.61 ng/ml, p<0.001). The serum concentration in OA patients was higher comparing with age-matched healthy controls (84.19±11.39 ng/ml) (p<0.05). A statistically significant association between YKL- 40 in synovial fluid and serum levels was shown. We determined a moderately positive linear relationship between the synovial level of the glycoprotein and the serum concentration. No association between the levels of inflammatory markers – erythrocyte sedimentation rate and C-reactive protein – and YKL-40 concentrations was detected. Our study revealed a strong relationship between YKL-40 in synovial fluid and GS US and feeble with PD US. YKL-40 correlated with inflammatory activity in knee joints and neovascularization detected by US.Conclusions: YKL-40 is involved in the pathogenesis of OA synovitis. Evaluation of YKL-40 levels in parallel with US might provide more sensitive and reliable information for the diagnosis and understanding of OA.

show abstract

“…Ultrasonography has also been proven as a useful tool in monitoring knee osteoarthritis treatment effectiveness [15] . Specialized ultrasound doctors will collect data via Philip HP SONOS 5500 ultrasound imaging machine.…”

Section: Musculoskeletal Ultrasoundmentioning

confidence: 99%

Effect of Acupotomy in Knee Osteoarthritis Patients: Study Protocol for A Randomized Controlled Trial

Lee

Huang

et al. 2020

Preprint

View full text Add to dashboard Cite

BackgroundSymptomatic knee osteoarthritis patients are common in China. Pharmacologic therapy is not the first recommendation because of its safety issues. Non-pharmacologic therapy, such as lifestyle adjustments, weight loss, and proper exercise is strongly recommended to use in knee osteoarthritis. But the adherance rate is very poor. Acupotomy therapy, as an effective treatment for knee osteoarthritis, is lack of high quality randomized controlled trials. This study set out to investigate the efficacy of acupotomy in patients with knee osteoarthritis.Methods136 patients will be enrolled in the First Affiliated Hospital of Guangzhou University of Chinese Medicine, and assigned into acupotomy group or sham acupotomy group according to the block randomization number. The acupotomy group will receive 2 sessions of acupotomy for 2 weeks(once a week). The sham group will receive 2 sessions of sham stimulation for 2 weeks༈once 2 week. All the patients will use indomethacin cream externally. The primary outcome is the WOMAC index and the secondary outcomes are VAS, plantar pressure distribution test, X-ray examination, musculoskeletal ultrasound, maximum knee circumference, and joint mobility. We will measure them at baseline, one week after the end of treatments, the third month and sixth month follow up.DiscussionAs we know, this is the first single-blinding and sham controlled design in acupotomy research. We aim to prove the efficacy of acupotomy in treating knee osteoarthritis.Trial registrationChinese Clinical Trial Registry: ChiCTR2000033047(2020-5-18).

show abstract

Role of Ultrasonography in Knee Osteoarthritis

Cited by 43 publications

References 39 publications

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis

Correlation between protein YKL-40 and ultrasonographic findings in active knee osteoarthritis

Effect of Acupotomy in Knee Osteoarthritis Patients: Study Protocol for A Randomized Controlled Trial

Contact Info

Product

Resources

About