Role of Ultra-Wide Field Imaging in the Management of Tubercular Posterior Uveitis

Abstract

UWF imaging is useful in the detection of peripheral pathologies in tubercular posterior uveitis that may influence management decisions, such as addition of immunosuppressive therapy or scatter laser photocoagulation.

Infectious uveitis: an Asian perspective

“…Ultra-wide field imaging of TB SLC: The relatively new ultra-wide field (UWF) imaging technique allows 200 degrees of the retina to be captured in a single image thereby allowing simultaneous capture of all retinal lesions in a single frame. As shown by Aggarwal et al, UWF imaging is a very useful tool in the management of IOTB as it helps to capture peripheral areas of retinal non-perfusion, active retinal vasculitis, neovascularization, and choroiditis lesions which would otherwise be missed on conventional fundus imaging [52][53][54]. UWF imaging revealed additional TB SLC lesions in 39 out of 44 eyes (88.6%) compared to conventional imaging.…”

“…UWF imaging revealed additional TB SLC lesions in 39 out of 44 eyes (88.6%) compared to conventional imaging. It has been shown to provide additional information in 90.9% of the eyes with TB posterior uveitis and affected management decisions in over 45% of the eyes [52].…”

“…Using conventional imaging, paradoxical worsening was reported in 14% patients after 2 to 6 weeks of initiation of ATT [37]. With UWF imaging, paradoxical worsening may be observed in over 36% patients after initiation of ATT [52,88,89]. In a series by Agarwal et al, OCT angiography was shown to be very useful in the detection of choriocapillaris alterations in patients of TB SLC developing paradoxical worsening [88].…”

Imaging in tuberculosis-associated uveitis

“…[456] Ultra-wide-field angiography reveals additional information on the extent of retinal vasculitis, retinal ischemia, and choroiditis lesions that can influence or change treatment options.…”

Post-infectious Uveitis

“…These and other seminal observations support a growing appreciation for the modulatory role of the intestinal microbiome in the pathogenesis of uveitis. [17][18][19] Five original articles [20][21][22][23][24] and one letter to the editor 25 in this issue of Ocular Immunology & Inflammation (OII) directly or indirectly address issues related to postinfectious uveitis.…”