Role of Type I Interferons during Mycobacterium tuberculosis and HIV Infections
Elsa Anes,
José Miguel Azevedo-Pereira,
David Pires
Abstract:Tuberculosis and AIDS remain two of the most relevant human infectious diseases. The pathogens that cause them, Mycobacterium tuberculosis (Mtb) and HIV, individually elicit an immune response that treads the line between beneficial and detrimental to the host. Co-infection further complexifies this response since the different cytokines acting on one infection might facilitate the dissemination of the other. In these responses, the role of type I interferons is often associated with antiviral mechanisms, whil… Show more
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