Role of transvaginal ultrasonography in diagnosing endometrial hyperplasia in pre- and post-menopause women

Shokouhi, Behrooz

doi:10.4103/0300-1652.170390

Cited by 14 publications

(10 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, pelvic scans showed no features suggestive of malignant transformation in any women in the group, which was confirmed by histology. The exact accuracy of TVUS in diagnose of endometrial hyperplasia is not known, and the reported sensitivity varies largely between 59.7 and 100% [26,27]. Many studies generally define an endometrial thickness lower than 5.0 mm as the normal cut-off value in postmenopausal women, as endometrial thickness of 3.0-4.0 mm in postmenopausal women reduces the chance of endometrial cancer to less than 1% [28][29][30].…”

Section: Discussionmentioning

confidence: 99%

The value of MRI in management of endometrial hyperplasia with atypia

et al. 2020

View full text Add to dashboard Cite

Background: The value of the magnetic resonance imaging (MRI) in the assessment of women with endometrial hyperplasia and its role in diagnosis of myometrial invasion or coexistence of cancer is not known. This study aimed to evaluate the accuracy and usefulness of MRI in the management of patients diagnosed on endometrial biopsy with complex endometrial hyperplasia with atypia (CEHA). Methods: A retrospective study of 86 cases diagnosed with endometrial hyperplasia with atypia on the initial endometrial biopsy in a tertiary university teaching hospital between 2010 and 2015 was carried out. The MRI accuracy in predicting malignant changes and influence the clinical management was compared among women who had either pelvic MRI, transvaginal ultrasound (TVUS), or no additional imagistic studies. Results: MRI was performed in 24 (28%) and TVUS in 11 (13%)cases, while 51 (59%) women had no additional imagistic studies. In the group of women with no imaging studies, 26/51 (51%) were surgically treated and 8/26 (31%) were diagnosed with endometrial cancer (EEC) stage 1a. In the group of women who had TVUS, 5/11 (45%) were surgically treated and none was diagnosed with EEC. In the group of women who underwent an MRI examination, 20/24 (83%) were surgically treated. Among these, 11/20 (55%) were diagnosed with EEC, 7 had EEC stage 1a, and 4 had EEC stage 1b. Although MRI was able to identify malignant changes with a good sensitivity (91.7%), it had a low specificity in characterisation of malignant transformation (8%). MRI correctly identified 31% of the stage 1a and 33% of the stage 1b endometrial cancer. Conclusion: In this study, we found a potential diagnostic value of MRI for identifying malignant transformation in patients with CEHA. However, pelvic MRI has a rather weak predictive value of myometrial invasion in women with CEHA and concurrent EEC. The diagnostic and therapeutic benefits of MRI assessment in patients with CEHA need further validation.

show abstract

Section: Discussionmentioning

confidence: 99%

The value of MRI in management of endometrial hyperplasia with atypia

et al. 2020

View full text Add to dashboard Cite

show abstract

“…19 The accuracy, sensitivity, specificity, PPV, and NPV were 88.25%, 90.7%, 84%, 97.7%, and 84% in premenopausal women in AUB patients specially in endometrial hyperplasia in their study. Aslam et al reported sensitivity and specificity of TVS 81.3%, 73.6% respectively.…”

Section: Abnormal Endometrial Finding On Tvsmentioning

confidence: 99%

Evaluation of abnormal uterine bleeding with transvaginal sonography and hysteroscopy in perimenopausal women

Choudhary¹,

Agrawal²,

Jain³

2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Abnormal uterine bleeding is defined as any deviation from the normal menstrual cycle this include change in regularity, frequency of menses, duration or amount of bleeding during or in between periods. Objective of present study was to evaluate abnormal uterine bleeding with transvaginal sonography and hysteroscopy in perimenopausal women.Methods: This study is conducted on women presenting to the gynecological OPD with complain of abnormal uterine bleeding in perimenopausal age group. A total of 50 patients were subjected to transvaginal sonography and Diagnostic hysteroscopy.Results: On TVS, out of total 50 patients, 50% patient showed normal endometrial finding. 24% Patient showed Endometrial hyperplasia, 14% Endometrial Polyp, 8% Submucosal fibroid, 4% Adenomyosis. On TVS, out of total 50 patient, 50% patient showed normal endometrial finding. 24% Patient showed endometrial hyperplasia, 14% endometrial Polyp, 8% submucosal fibroid, 4% adenomyosis. Out of total 50 patients, 28 (56%) showed normal endometrial finding.20% cases showed endometrial Hyperplasia, 16% showed endometrial Polyp, 8% showed submucosal fibroid. Sensitivity, specificity, PPV, NPV of endometrial hyperplasia – 81.81%, 92.3%, 75%, 94.73% respectively.Conclusions: Transvaginal sonography has a moderate diagnostic accuracy in detecting endometrial hyperplasia and other intrauterine pathology. TVS is safe, acceptable and easily available & is noninvasive. It should be used as 1st line diagnostic tool in patients with AUB in perimenopausal women. Hysteroscopy has important tool in the diagnosis of various endometrial and intrauterine lesions TVS and hysteroscopy should be employed hand in hand in evaluation of AUB.

show abstract

“…14,15 In present study the sensitivity, specificity, PPV, NPV for diagnosis of endometrial hyperplasia on TVS was 81.81, 94.43%, 90%, 95% which correlate with Shokouhi B. 16 The accuracy, sensitivity, specificity, PPV, and NPV were 88.25%, 90.7%, 84%, 97.7%, and 84% in premenopausal women in AUB patient specially in endometrial hyperplasia. Aslam reported sensitivity and specificity 81.3%, 73.6% respectively.…”

mentioning

confidence: 75%

Evaluation of abnormal uterine bleeding with transvaginal sonography

Jain

Chakraborty

2017

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Abnormal uterine bleeding (AUB) is an important cause of health hazard in perimenopausal women. Accurate diagnosis for the causative factor of AUB in this age group is of utmost importance so that appropriate management can be established. Objective pf present study was to estimate the diagnostic accuracy, efficacy, sensitivity and specificity of transvaginal ultrasound in evaluation of uterine cavity lesion in perimenopausal women with abnormal uterine bleedingMethods: This is a prospective study. This study was carried out in the Department of Obstetrics and Gynecology of Mahatma Gandhi Medical College and Hospital, Jaipur. We included 50 patients of perimenopausal age group who attended the gynecology department with the complaint of AUB. After selecting the patients who fulfill the eligibility criteria in the OPD detailed clinical history, obstetrical and gynecological history taken and detail clinical examination was done as per proforma followed by TVS.Results: In the present study, maximum no of cases between age group of 40 to 44 with 48%, and 38% of cases between age group of 45-49 yr. This suggests abnormal uterine bleeding is common in perimenopausal women. In present study overall sensitivity, specificity, PPV, NPV of TVS were 76%, 94%, 76% and 94%.Conclusions: In conclusion, abnormal uterine bleeding which often prevails as an important and common gynecological ailment. The Sensitivity, Specificity, PPV, NPV of TVS was 76%, 94%, 76% and 94%. The result showed that Transvaginal sonography has a moderate diagnostic accuracy in detecting endometrial hyperplasia and other intrauterine pathology. TVS is safe, acceptable and easily available in most secondary and tertiary care setting and is noninvasive. It should be continued as 1st line diagnostic tool in patients with AUB in perimenopausal women.

show abstract

Role of transvaginal ultrasonography in diagnosing endometrial hyperplasia in pre- and post-menopause women

Cited by 14 publications

References 27 publications

The value of MRI in management of endometrial hyperplasia with atypia

The value of MRI in management of endometrial hyperplasia with atypia

Evaluation of abnormal uterine bleeding with transvaginal sonography and hysteroscopy in perimenopausal women

Evaluation of abnormal uterine bleeding with transvaginal sonography

Contact Info

Product

Resources

About