Role of Transbronchial Needle Core Biopsy in the Diagnosis of Mediastinal Diseases

Galluccio, Giovanni; Palazzolo, M; Battistoni, Paolo; Iacono, Raffaele Dello; Batzella, Sandro; Caterino, Umberto; Lucantoni, Gabriele

doi:10.1097/lbr.0000000000000253

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Thoracoscopy is considered a standard diagnostic modality, but less invasive techniques have emerged as potential alternatives, including transthoracic needle aspiration and EBUS with needle aspiration ( 24 ). In the present study, in the 106 cases (13.3%) that were unable to undergo surgical intervention due to medical contraindications or advanced disease, FNA and Tru-cut biopsy were conducted to obtain tissue for histological diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Resectability in bronchogenic carcinoma: A single‑center experience

Marie¹,

Jaber

Ahmed³

et al. 2023

Oncol Lett

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Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability.

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Section: Discussionmentioning

confidence: 99%

Resectability in bronchogenic carcinoma: A single‑center experience

Marie¹,

Jaber

Ahmed³

et al. 2023

Oncol Lett

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The role of needle core biopsies in the evaluation of thymic epithelial neoplasms

Suster

2020

Journal of the American Society of Cytopathology

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The role of bronchoscopy in the diagnosis of airway disease

Paradis¹,

Dixon²,

Tieu³

2016

J. Thorac. Dis.

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Endoscopy of the airway is a valuable tool for the evaluation and management of airway disease. It can be used to evaluate many different bronchopulmonary diseases including airway foreign bodies, tumors, infectious and inflammatory conditions, airway stenosis, and bronchopulmonary hemorrhage. Traditionally, options for evaluation were limited to flexible and rigid bronchoscopy. Recently, more sophisticated technology has led to the development of endobronchial ultrasound (EBUS) and electromagnetic navigational bronchoscopy (ENB). These technological advances, combined with increasing provider experience have resulted in a higher diagnostic yield with endoscopic biopsies. This review will focus on the role of bronchoscopy, including EBUS, ENB, and rigid bronchoscopy in the diagnosis of bronchopulmonary diseases. In addition, it will cover the anesthetic considerations, equipment, diagnostic yield, and potential complications.

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Role of Transbronchial Needle Core Biopsy in the Diagnosis of Mediastinal Diseases

Abstract: Our results confirm that, in selected cases, transbronchial rigid core biopsy could be considered a safe and valid alternative technique to more invasive surgical approach in the diagnosis of mediastinal diseases.

Cited by 3 publications

References 16 publications

Resectability in bronchogenic carcinoma: A single‑center experience

Resectability in bronchogenic carcinoma: A single‑center experience

The role of needle core biopsies in the evaluation of thymic epithelial neoplasms

The role of bronchoscopy in the diagnosis of airway disease

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