With an effective Lagrangian approach, we give a full analysis on the NN → NNππ and pp → pnπ + reactions for proton beam energy from 1 to 1.5 GeV. The results are very consistent with the experiment data from CELSIUS, KEK, COSY, and so on. Based on these results, we consider theNN →NNππ andpp →pnπ + for proton beam energy up to 4 GeV. Compare to the pp collisions, there are many benefits to study N * resonances in these two reactions. And for the high proton beam energy up to 15 GeV, we consider some new resonances with hidden charm which are definitely beyond three constituent quarks model in thepp →ppJ/ψ andpp →ppη c , where there are very nice places to find these new N * cc . The predicted results aboutpp collisions can be looked for at the forthcoming PANDA/FAIR experiments.