Role of the OH and NH vibrational groups in polysaccharide-nanocomposite interactions: A FTIR-ATR study on chitosan and chitosan/clay films

Branca, C.; D’Angelo, Giovanna; Crupi, C.; Khouzami, Khaoula; Rifici, S.; Ruello, Giovanna; Wanderlingh, U.

doi:10.1016/j.polymer.2016.07.086

Cited by 233 publications

(99 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Figure 3 also reveals that the antibacterial performance of the composite film against E. coli is better than that against S. aureus. The same amount of CS exhibited stronger antibacterial performance against E. coli than against S. aureus, which is consistent with the conclusions of Ashraf et al [50]. Being an organic antibiotic, CS can reduce or prevent bacterial adhesion and biofilm formation.…”

Section: Analysis Of the Antibacterial Activitysupporting

confidence: 91%

Preparation and Properties of Sodium Carboxymethyl Cellulose/Sodium Alginate/Chitosan Composite Film

2018

View full text Add to dashboard Cite

A sodium alginate/chitosan solution was prepared by dissolving sodium alginate, chitosan, and glycerol in an acetic acid solution. This solution was then combined with a sodium carboxymethyl cellulose solution and the mixture was cast onto a glass plate and dried at a constant temperature of 60 • C. Then, a carboxymethyl cellulose/sodium alginate/chitosan composite film was obtained by immersing the film in a solution of a cross-linking agent, CaCl 2 , and air-drying the resulting material. First, the most advantageous contents of the three precursors in the casting solution were determined by a completely random design test method. Thereafter, a comprehensive orthogonal experimental design was applied to select the optimal mass ratio of the three precursors. The composite film obtained with sodium alginate, sodium carboxymethyl cellulose, and chitosan contents of 1.5%, 0.5%, and 1.5%, respectively, in the casting solution displayed excellent tensile strength, water vapor transmission rate, and elongation after fracture. Moreover, the presence of chitosan successfully inhibited the growth and reproduction of microorganisms. The composite film exhibited antibacterial rates of 95.7% ± 5.4% and 93.4% ± 4.7% against Escherichia coli and Staphylococcus aureus, respectively. Therefore, the composite film is promising for antibacterial food packaging applications.

show abstract

Section: Analysis Of the Antibacterial Activitysupporting

confidence: 91%

Preparation and Properties of Sodium Carboxymethyl Cellulose/Sodium Alginate/Chitosan Composite Film

2018

View full text Add to dashboard Cite

show abstract

“…The composite films also exhibited rapid initial swelling followed by slow mass loss. Similar findings were previously reported for chitosan‐montmorillonite composite films . However, the swelling was less intensive and the mass loss was slower in a comparison to the corresponding CS films implying stabilization effect of HNTs on CS‐based hydrogel network.…”

Section: Resultssupporting

confidence: 88%

Functionality of chitosan‐halloysite nanocomposite films for sustained delivery of antibiotics: The effect of chitosan molar mass

Čalija

Milić

Milašinović

et al. 2019

J of Applied Polymer Sci

View full text Add to dashboard Cite

This study was designed to investigate functionality of tetracycline‐loaded chitosan‐halloysite nanocomposite films, with focus on evaluating the influence of chitosan molar mass on films applicability for sustained local antibiotic delivery. The films were prepared by casting and solvent evaporation using low, medium, and high molar mass chitosan. SEM analysis revealed compact, nonporous and rough surface of the nanocomposite films due to the presence of halloysite agglomerates and tetracycline crystals. Increasing chitosan molar mass led to higher values of elongation at break (from 21.65 ± 2.65 to 34.48 ± 2.34%), tensile strength (from 134.8 ± 13.21 to 246.36 ± 14.69 MPa), and elastic modulus (from 633.79 ± 128.37 to 716.55 ± 60.76 MPa) of the nanocomposite films. FT‐IR, XRPD, and thermal analyses confirmed molar mass dependent chitosan‐halloysite interactions and improved thermal stability of the nanocomposite films in comparison with chitosan films. The nanocomposite films released tetracycline in a sustained manner, with the slowest release achieved from the films consisting of low molar mass chitosan. Chitosan molar mass was confirmed to be a functionality‐related characteristic of chitosan‐halloysite nanocomposite films as potential sustained‐release carriers for topical delivery of antibiotics. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48406.

show abstract

“…The hysteris loop of the MNP [Figure (b)] confirms its superparamagnetic behavior. The major peaks of chitosan [Figure (a)], vancomycin [Figure (b)] and MNP [Figure (a)] are prominent in XRD of the chitosan‐MNP microbeads [Figure (c)], supporting the presence of these constituents in the DDS . It was further affirmed by FTIR (Figure ) which showed amine groups and hydroxyl groups corresponding to chitosan and vancomycin, respectively.…”

Section: Discussionmentioning

confidence: 72%

“…16,17 The hysteris loop of the MNP [ Figure 6 Figure 9(c)], supporting the presence of these constituents in the DDS. 18,19 It was further affirmed by FTIR ( Figure 8) which showed amine groups and hydroxyl groups corresponding to chitosan and vancomycin, respectively. The C-O-C stretching confirms the inclusion of polyethylene glycol in the DDS.…”

Section: Discussionmentioning

confidence: 77%

Magnetic stimulus responsive vancomycin drug delivery system based on chitosan microbeads embedded with magnetic nanoparticles

et al. 2017

View full text Add to dashboard Cite

Local antibiotic delivery can overcome some of the shortcomings of systemic therapy, such as low local concentrations and delivery to avascular sites. A localized drug delivery system (DDS), ideally, could also use external stimuli to modulate the normal drug release profile from the DDS to provide efficacious drug administration and flexibility to healthcare providers. To achieve this objective, chitosan microbeads embedded with magnetic nanoparticles were loaded with the antibiotic vancomycin and stimulated by a high frequency alternating magnetic field. Three such stimulation sessions separated by 1.5 h were applied to each test sample. The chromatographic analysis of the supernatant from these stimulated samples showed more than approximately 200% higher release of vancomycin from the DDS after the stimulation periods compared to nonstimulated samples. A 16-day long term elution study was also conducted where the DDS was allowed to elute drug through normal diffusion over a period of 11 days and stimulated on day 12 and day 15, when vancomycin level had dropped below therapeutic levels. Magnetic stimulation boosted elution of test groups above minimum inhibitory concentration (MIC), as compared to control groups (with no stimulation) which remained below MIC. The drug release from test groups in the intervals where no stimulation was given showed similar elution behavior to control groups. These results indicate promising possibilities of controlled drug release using magnetic excitation from a biopolymer-based DDS. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2169-2176, 2018.

show abstract

Role of the OH and NH vibrational groups in polysaccharide-nanocomposite interactions: A FTIR-ATR study on chitosan and chitosan/clay films

Cited by 233 publications

References 44 publications

Preparation and Properties of Sodium Carboxymethyl Cellulose/Sodium Alginate/Chitosan Composite Film

Preparation and Properties of Sodium Carboxymethyl Cellulose/Sodium Alginate/Chitosan Composite Film

Functionality of chitosan‐halloysite nanocomposite films for sustained delivery of antibiotics: The effect of chitosan molar mass

Magnetic stimulus responsive vancomycin drug delivery system based on chitosan microbeads embedded with magnetic nanoparticles

Contact Info

Product

Resources

About