Role of the auxiliary ligand in determining the genotoxicity and mode of cell death of thiosemicarbazone Pd(ii) complexes

Abstract

We report how the cytotoxicity, mode of death and genotoxic effect of a series of square planar Pd(ii) complexes are determined by the auxiliary ligand coupled to the Pd(ii) ion, which is chelated by the tridentate thiosemicarbazone ligand.