Role of tamsulosin in treatment of patients with steinstrasse developing after extracorporeal shock wave lithotripsy

Resim, Sefa; Ekerbiçer, Hasan Çetin; Çiftçi, Ahmet Burak

doi:10.1016/j.urology.2005.05.029

Cited by 87 publications

(49 citation statements)

References 21 publications

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“…Resim et al [29] studied 67 patients with steinstrasse after renal SWL and found that the tamsulosin nonsignificantly increased the rate of stone clearance relative to the controls (75 vs. 65.7%; p < 0.05). In contrast, Moursy et al [30] studied 88 patients with steinstrasse after renal SWL and reported a significant increase in the rate of stone clearance with tamsulosin compared to the controls (72.7 vs. 56.8%; p = 0.017).…”

Section: Discussionmentioning

confidence: 99%

Role of Tamsulosin Therapy after Extracorporeal Shockwave Lithotripsy for Renal Stones: Randomized Controlled Trial

Ahmed

Shalaby²,

El-Feky³

et al. 2016

Urol Int

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Introduction: To evaluate the efficacy of adjunctive tamsulosin therapy after extracorporeal shockwave lithotripsy (SWL) for renal stones. Materials and Methods: This prospective study was conducted on patients who underwent single-session SWL for solitary renal stone less than 20 mm. Post-SWL, patients were randomly divided into 2 groups; the tamsulosin group (TG), received a daily dose of tamsulosin 0.4 mg, for a maximum of 12 weeks, with post-SWL traditional analgesia and control group (CG), received the traditional analgesia alone. Results: The study enrolled 271 patients and eventually only 249 (123 in TG and 126 in CG) completed the study. The overall stone free rate was 73.5%: 78.0% in TG and 69.0% in CG (p = 0.108). In TG, 8.1% of patients experienced at least one episode of acute renal/ureteral colic compared with 19.8% of controls (p = 0.008). The mean cumulative analgesia dosage per subject was 313 mg in TG and 346 mg in CG (p < 0.001). Overall, 14 patients developed steinstrasse and 6 of them (all in CG) needed urgent intervention (p = 0.031). Conclusions: Daily tamsulosin therapy does not enhance the clearance of stone fragments but decreases the pain episodes, analgesia dosage and need for adjuvant intervention after SWL for renal stones.

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Section: Discussionmentioning

confidence: 99%

Role of Tamsulosin Therapy after Extracorporeal Shockwave Lithotripsy for Renal Stones: Randomized Controlled Trial

Ahmed

Shalaby²,

El-Feky³

et al. 2016

Urol Int

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“…p [ 0.05) [29]. In contrast, 88 patients with unilateral steinstrasse following SWL were randomized to receive analgesics or tamsulosin (0.4 mg) for a maximum of 4 weeks in addition to analgesic.…”

Section: Discussionmentioning

confidence: 99%

Tamsulosin and doxazosin as adjunctive therapy following shock-wave lithotripsy of renal calculi: randomized controlled trial

et al. 2011

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Alpha-blockers have been established as medical expulsive therapy for urolithiasis. We aimed to assess the effect of tamsulosin and doxazosin as adjunctive therapy following SWL for renal calculi. We prospectively included 150 patients who underwent up to four SWL sessions for renal stones from June 2008 to 2009. Patients were randomized into three groups of 50 patients each, group A (phloroglucinol 240 mg daily), group B (tamsulosin 0.4 mg once daily plus phloroglucinol), and group C (doxazosin 4 mg plus phloroglucinol). The treatment continued up to maximum 12 weeks. Patients were evaluated for stone expulsion, colic attacks, amount of analgesics and side-effects of alpha-blockers. There were no significant differences between the groups regarding stone expulsion rates (84; 92 and 90%, respectively). The mean expulsion time of tamsulosin was significantly shorter than both control group (p = 0.002) and doxazosin (p = 0.026). Both number of colic episodes and analgesic dosage were significantly lower with tamsulosin as compared to control and doxazosin. Steinstrasse was encountered in 10 (6.7%) patients with no significant difference between the groups. 16 patients on tamsulosin and 21 on doxazosin experienced adverse effects related to postural hypotension. Moreover, 2 (4%) patients in the tamsulosin group reported ejaculatory complaints. In conclusion, adjunction of tamsulosin or doxazosin after SWL for renal calculi decreases the time for stone expulsion, amount of the analgesics and number colic episodes. There was no benefit regarding the overall stone expulsion rate. The side-effects of these agents are common and should be weighted against the benefits of their usage.

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“…Tamsulosin increases distal ureter stone passage shortens the time to stone-free status compared with controls. Tamsulosin is more efficacious for distal ureter stones (nifedipine seems preferable for proximal ureter stones), is also beneficial for the clearance of steinstrasse (not statistically significant), reduces the number of ureteral colic episodes and the severity of pain in the patients who developed steinstrasse after shockwave lithotripsy [29] .…”

Section: Operator Variablesmentioning

confidence: 98%

ESWL Prediction of Outcome and Failure Prevention

et al. 2007

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Based on our own experiences and a review of the recent literature, this article evaluates recent developments in predicting outcomes and failures of shockwave lithotripsy when treating patients with urinary tract stones. After a detailed MEDLINE research, the authors identified several variables that influence and predict extracorporeal shockwave lithotripsy (ESWL) success. These variables may be categorized as stone variables, patient variables and operator variables. Only multivariate analysis on a large number of homogenous patients may offer an objective evaluation of the factors conditioning ESWL outcome.

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Role of tamsulosin in treatment of patients with steinstrasse developing after extracorporeal shock wave lithotripsy

Cited by 87 publications

References 21 publications

Role of Tamsulosin Therapy after Extracorporeal Shockwave Lithotripsy for Renal Stones: Randomized Controlled Trial

Role of Tamsulosin Therapy after Extracorporeal Shockwave Lithotripsy for Renal Stones: Randomized Controlled Trial

Tamsulosin and doxazosin as adjunctive therapy following shock-wave lithotripsy of renal calculi: randomized controlled trial

ESWL Prediction of Outcome and Failure Prevention

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