Role of NF‐κB in cardiac changes of obstructive sleep apnoea rabbits treated by mandibular advancement device
Wenjing Kang,
Dechao Zhu,
Shilong Zhang
et al.
Abstract:BackgroundObstructive sleep apnoea (OSA) is an independent risk factor for cardiovascular diseases. We aimed to investigate the role of nuclear factor‐kappa B (NF‐κB) in the changes of cardiac structures in OSA rabbits treated by mandibular advancement device (MAD).MethodsEighteen male New Zealand white rabbits aged 6 months were randomly divided into three groups: control group, group OSA and group MAD. Hyaluronate gel was injected into the soft palate of the rabbits in group OSA and group MAD to induce OSA. … Show more
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