Role of renal Duplex ultrasonography in evaluation of hepatorenal syndrome

Abstract

Background Hepatorenal syndrome is a potentially fatal complication of advanced liver disease. Markers for early diagnosis and identification of high-risk patients are lacking. Our aim was to evaluate the role of renal Duplex ultrasonography in the diagnosis and early prediction of hepatorenal syndrome. This study included 50 patients. Clinical assessment, liver function tests, hepatitis C virus antibody, kidney function tests, and abdominal and renal color Duplex ultrasound were done to all subjects. Results Univariate regression analysis for hepatorenal syndrome showed a statistically significant positive correlation with the Model For End-Stage Liver Disease score (p-value <0.0001) and renal artery hilum resistivity index (p-value = 0.0017). Logistic multivariable regression analysis proved that the renal artery hilum resistivity index was an independent predictor of hepatorenal syndrome. Renal artery hilum resistivity index can be used as a predictor of hepatorenal syndrome with 100% sensitivity and 66.7% specificity with a cut-off value > 0.77. Conclusion The renal resistive index could be a good predictor of hepatorenal syndrome.

Relation between renal resistive index and renal function in septic patients developing acute kidney injury 2

“…In our study RRI was in a positive correlation with serum creatinine (P < 0.05) and mean creatinine in patients with persistent AKI was significantly higher (P < 0.04). Similar to our results, Mohamad Sherif Mogawer et al (2021) (10) conducted a study on 50 patients suffering from child C liver cirrhosis and known normal baseline serum creatinine within one year before AKI. They showed that RI can predict hepato-renal syndrome (HRS) with 100% sensitivity and 67% specificity (cut off value > 0.77).…”

“…RI is a sonographic index of intrarenal arteries and is measured as follows: (maximum systolic velocity−minimum-diastolic-velocity)/maximum systolic velocity. The normal range of RI is 0.50-0.70.For adults, RI value of 0.70 indicates normal renal vascular resistance (RVR), and all measures above 0.70 indicate increased RVR [10]. RRI was measured for all patients on admission and follow-up was done after 48 h, and the patients were followed till hospital discharge to detect correlation to outcome.…”

The Potentials of Contrast-Free Renal ASL MRI Perfusion in the Diagnosis and Dynamic Follow-Up of Renal Lesions in Patients with Diffuse Liver Diseases

“…Это обусловлено высокой частотой развития дан ного осложнения, особенно у больных с тяжелым течением патологии печени. Так, по данным ис следований, от 25% до 50% пациентов с циррозом печени, поступающих на госпитальное лечение после эпизода декомпенсации, имеют признаки ГРС [10,11] УЗИ с допплеровским сканированием сосу дов является операторозависимым методом ис следования, однако при умелом использовании также с высокой эффективностью позволяет обна ружить признаки ГРС, особенно в развернутой ста дии [9,14].…”