Role of Radiation Therapy in Carcinoma of the Hypopharynx

Ahmad, Khurshid; Fayos, Juan V.

doi:10.3109/02841868409135980

Cited by 16 publications

(1 citation statement)

References 34 publications

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“…According to the literature, radiotherapy alone, administered at 60-75 Gy/6-7.5 weeks for T2 disease achieved 70%-80ϩ% of local control at 2 to 5 years for cancer of the oropharynx, 25-33 60%-75ϩ% for the larynx, [34][35][36][37] and 40%-70ϩ% for the hypopharynx. [38][39][40][41][42][43] The reported local control rates for patients with T3-T4 tumors, and survival rates for stage III/IV non-nasopharyngeal HNSCC varied widely, as shown in Table 1. 4, Apparently these outcomes were influenced by considerable differences in patient selection, staging criteria, and accuracy of staging of the disease, depending on imaging modalities available at the time of these reports.…”

Section: Treatment Results After Radiotherapy Alonementioning

confidence: 96%

Chemoradiotherapy for head and neck cancer: current status and perspectives

Kawashima

2004

Int J Clin Oncol

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Chemoradiotherapy for head and neck cancer has achieved remarkable progress in the past two decades. This progress has resulted in efforts to redefine the standard of care for patients with this disease. A brief review of the history of current chemoradiotherapy was conducted to clarify the rationale for this approach. An attempt was made to present problems that remain to be solved. The review showed that chemoradiotherapy for head and neck cancer is now becoming a vital treatment option for patients with advanced disease. Currently available and upcoming data are about to clarify important issues regarding proper patient selection, standard procedures, management of toxicities, ultimate cure, and quality of life. This newly developed and promising treatment option has, however, confounding problems to be solved. Meticulous collaboration in an experienced multidisciplinary team is required to address these problems and to spread this approach in daily clinical practice.

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