Role of post-operative radiation therapy in single brain metastasis from clear cell sarcoma in children: a case report with systemic review

Abstract

IntroductionBrain metastasis is a common oncologic problem in adults but is relatively uncommon in children with solid tumors. In fact, approximately 25-35% of all adult cancer patients with solid tumors will develop parenchymal intracranial metastasis whereas only 2.5% to 4.5% of children will do [1][2][3][4][5]. Brain metastasis of clear cell sarcoma of the kidney occurs in less than 5% of cases during the follow-up [6,7]. Because of the relative rarity of this particular entity, information regarding management and prognosis are still missing. Trough the report of

Brain metastases with unusual MRI features in an infant with relapsed clear cell sarcoma of the kidney: A case report

“…The presence or absence of peritumoral vasogenic edema was not mentioned in those reports. 3,5 The absence of peritumoral edema in a metastatic brain lesion from CCSK has been reported so far by Shajpaul et al 4 A single large-sized frontal hemispheric metastatic lesion, in that case, showed no tumor-associated edema and no contrast-enhancement. Those features have been attributed to the poor vascularity and cellularity of that metastatic lesion by the authors, reflecting the histopathology of the primary tumor.…”