2016
DOI: 10.3126/jpn.v6i12.16290
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Role of pleural fluid adenosine deaminase activity and lymphocytosis in the etiological diagnosis

Abstract: Background: Pleural effusion is a common medical condition with many possible underlying etiologies. However, Tuberculosis is the most common cause of pleural effusion especially in countries like Nepal. Pleural fluid lymphocytosis is seen in tuberculosis, malignancy and few auto-immune diseases. Adenosine Deaminase activity (ADA) level in tubercular pleural effusion is markedly increased compared to non-tubercular effusions. ADA estimation being a simple colorimetric method is suitable for the rapid diagnosis… Show more

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“…with increase in NPV of 100% with pleural fluid lymphocyte [23] counts. A study by Mathur PC et al had sensitivity and negative predictive value of 100% for ADA test which almost [8] correlates with the present study.…”
Section: Table I: Pleural Fluid Ada Levels In Tuberculous and Non Tub...mentioning
confidence: 91%
See 1 more Smart Citation
“…with increase in NPV of 100% with pleural fluid lymphocyte [23] counts. A study by Mathur PC et al had sensitivity and negative predictive value of 100% for ADA test which almost [8] correlates with the present study.…”
Section: Table I: Pleural Fluid Ada Levels In Tuberculous and Non Tub...mentioning
confidence: 91%
“…In the present study, among 59 cases of Tubercular pleural effusion, 58 cases had Pleural fluid lymphocyte count ≥ 50% and one case had <50% of total count. Among 51 cases of Nontubercular pleural effusion, 17 cases showed Pleural fluid lymphocyte count ≥ 50% and 34 cases had <50% .More than 50% of lymphocytes in pleural effusion can be seen in malignancy, cardiac failure, lymphoma, chronic rheumatoid pleurisy, sarcoidosis and late post coronary artery bypass [22][23][24][25][26][27] graft surgery effusions.…”
Section: Table I: Pleural Fluid Ada Levels In Tuberculous and Non Tub...mentioning
confidence: 99%