Role of Platelet-rich Plasma in the Management of Androgenetic Alopecia

Chaudhari, Nitin D; Dash, Kedarnath; Deshmukh, Palak

doi:10.4103/0974-7753.111222

Cited by 15 publications

(7 citation statements)

References 8 publications

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“…Uebel propose en 2006 de faire baigner les unités folliculaires dans du PRP avant de les implanter et observe une augmentation du taux de prise de ces greffes 9 . A partir de 2011, apparaissent les premiers articles proposant l'injection directe de PRP dans les zones alopéciques pour le traitement de l'alopécie androgénétique 10,11 . En fonction de variations de la préparation du PRP, on obtient des PRP différents : L-PRP (Leucocyteand platelet-rich plasma) si il contient encore des globules blancs, P-PRP (Pure-PRP) s'il n'en contient plus.…”

Section: Le Prp (Platelet-rich Plasma)unclassified

See 1 more Smart Citation

Injection of PRP (Platelet-rich plasma) as a treatment for androgenetic alopecia : a systematic review of the literature

Oth¹,

Stene²,

Glineur³

et al. 2018

Rev Med Brux

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Section: Le Prp (Platelet-rich Plasma)unclassified

“…31 articles ont donc été examinés, 24 articles ont été rejetés ne répondant pas aux critères d'inclusion 9,10,12,13,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] . 7 articles ont donc finalement été inclus dans cette revue systématique 8,36-41 (figure 2).…”

Section: Sélection Des Articlesunclassified

Injection of PRP (Platelet-rich plasma) as a treatment for androgenetic alopecia : a systematic review of the literature

Oth¹,

Stene²,

Glineur³

et al. 2018

Rev Med Brux

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“…PRP'de trombosit sayısı standart olmamasına rağmen (kullanılan PRP kitine göre sayı değişebilir), uygulanan PRP'nin etkili olması için ortalama trombosit sayısı 1 milyondan fazla (yaklaşık 7 kat) olması gereklidir 12 . Trombositlerin α-granüllerinde bulunan büyüme faktörleri, kemokinler ve sitokinlerden oluşan bir grup proteinin ortama salınmasına neden olur 13 (Tablo 2). Bu büyüme faktörlerinden oluşan kokteyl, doku tamiri ve rejenerasyonuna neden olmaktadır.…”

Section: Alopesi Tedavisinde Trombositten Zengin Plazmaunclassified

“…Ayrıca saç gelişiminde potent stimülatör olan FGF-7 (fibroblast büyüme faktörü) ve betakateninin dermal papilla hücrelerinde yeniden düzenlendiği saptanmıştır. PRP uygulanan grupta kontrol grubuna kıyasla daha hızlı sürede telogen evrede anagen evreye geçiş olduğu gözlenmiştir 13,17 .…”

Section: Androgenetik Alopeside Trombositten Zengin Plazmaunclassified

Mesotherapy and platelet-rich plasma for the treatment of hair loss

Gökdemir¹

2014

TURKDERM

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Hair loss often significant impact on quality of life, including loss of self-confidence and self-esteem. However, treatment of hair loss is frustrating for both patients and doctors. Mesotherapy and platelet-rich plasma have recently become advertised method for the treatment of different types of alopecia. The efficacy of these methods in hair loss is controversial in view of lack of documented evidence. It was reviewed the data about the efficacy, safety and treatment protocols of mesotherapy and platelet-rich plasma in patients with hair loss.

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“…It is a common dermatological disorder affecting both men and women, with significant negative impact on their social and psychological well being. [1] It commonly begins by 20 years of age and affects nearly 50% of men by the age of 50 years. [2] Platelet rich plasma(PRP) and percutaneous collagen induction or skin needling have recently been used _______________________________ *Correspondence Dr.Shivani Ranjan Senior Resident, Department of Dermatology, Veneorology, Leprology, Ascoms Hospital, Sidhra, Jammu, J&K, India E Mail: drshivaniranjan@rocketmail.com separately for hair stimulation both for male and female AGA.…”

Section: Introductionmentioning

confidence: 99%

A study of the efficacy of skin needling and platelet rich plasma in the treatment of androgenetic alopecia

Ranjan¹,

Gupta²,

Gupta³

2017

APJHS

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Background: Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma that may be useful in the treatment of androgenetic alopecia (AGA). Its action depends on the released growth factors from platelets. Skin needling is a technique that uses a sterile dermaroller to puncture the skin and release growth factors. The combination of Skin needling and PRP should enhance the efficacy of both modalities. Objective: To establish the effectiveness of the combined use of Skin needling and PRP in AGA treatment. Method: The study enrolled 10 patients of AGA. The hair pull test was performed before each treatment session. PRP therapy with skin needling was given to them at monthly intervals for 6 months. The effects of therapy were evaluated based on clinical examination, hair pull test, photographic assessment and patient's satisfaction. Result: Before treatment, 80 % of our patients had a positive hair pull test with a mean number of 9 hairs which turned to be negative only after the third session. After 6 months, there was an overall improvement in hair density with the response of grade +2 in 8 patients and +1 in 2 patients on the standardised 7-point evaluation scale. 3 patients rated response as grade 4, 5 patients as grade 3 and 2 patients as grade 2 on patients' subjective evaluation of hair growth. Pain during the procedure and sensible scalp afterwards were the major complaints which subsided in 2-3 days. Conclusion: PRP combined with skin needling is a safe and effective treatment and can be considered as an alternative for management of AGA.

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Role of Platelet-rich Plasma in the Management of Androgenetic Alopecia

Cited by 15 publications

References 8 publications

Injection of PRP (Platelet-rich plasma) as a treatment for androgenetic alopecia : a systematic review of the literature

Injection of PRP (Platelet-rich plasma) as a treatment for androgenetic alopecia : a systematic review of the literature

Mesotherapy and platelet-rich plasma for the treatment of hair loss

A study of the efficacy of skin needling and platelet rich plasma in the treatment of androgenetic alopecia

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