Role of Platelet Rich Plasma in Treatment of Bed/Pressure Sores in Patients With Orthopedic Injuries

Abstract

Aim: To assess the effect of Platelet rich plasma (PRP) on healing of bed/pressure sores among immobilized orthopaedic patients. A total of 138 patients with orthopaedic injuries under immobilization for >15 days to 5Method: years with presence of bed sores were enrolled in the study. Nature of wound (acute/chronic), duration of immbolization, wound and wound size was noted. Blood samples were obtained from all the patients and autologous PRP was prepared. Each patient received 5 ml of autologous PRP directly at the wound site. The process was repeated at every 4th day till achievement of >50% reduction or till day 60th. Final outcome was noted in terms of failure (<50% reduction), partial resolution (>50% reduction) and complete resolution (complete wound healing). Data was analysed using Independent samples 't'-test. Mean age of patients was 39.89±17.07 years and majority were males (75.4%) There were a totalResults: of 169 wounds. There was a dominance of acute wounds (79.9%). Mean wound size was 62.17±115.92 cm2. Mean duration of immobility was 98.41±40.31 days. Mean number of PRP infiltrations was 4.30±2.18. At final follow up 127 (75.1%) had complete resolution and remaining 42 (24.9%) had <50% reduction in wound size. No significant difference in wound size was observed between chronic and acute wounds at different follow-up intervals. PRP proved to beConclusion: effective in healing of bed sores of both chronic as well as acute origin in immobilized orthopaedic patients.