Role of Penile Prosthesis in Priapism: A Review

Abstract

Ischemic priapism is a urological emergency that has been associated with long-standing and irreversible adverse effects on erectile function. Studies have demonstrated a linear relationship between the duration of critically ischemic episodes and the subsequent development of corporal fibrosis and irreversible erectile function loss. Placement of a penile prosthesis is a well-established therapeutic option for the management of erectile dysfunction secondary to ischemic priapism, and will be the focus of this review. Review of the current literature demonstrates a growing utilization of penile prostheses in the treatment of erectile dysfunction secondary to ischemic priapism. Unfortunately, there is a paucity of randomized-controlled trials describing the use of prosthesis in ischemic priapism. As a result, there is a lack of consensus regarding the type of prosthesis (malleable vs. inflatable), timing of surgery (acute vs. delayed), and anticipated complications for each approach. Both types of prostheses yielded comparable complication rates, but the inflatable penile prosthesis have higher satisfaction rates. Acute treatment of priapism was associated with increased risk of prosthetic infection, and could potentially cause psychological trauma, whereas delayed implantation was associated with greater corporal fibrosis, loss of penile length, and increased technical difficulty of implantation. The paucity of high-level evidence fuels the ongoing discussion of optimal use and timing of penile prosthesis implantation. Current guidance is based on consensus expert opinion derived from small, retrospective studies. Until more robust data is available, a patient-centered approach and joint decision-making between the patient and his urologist is recommended.

Priapism in a Healthy Male: A Rare Side Effect of Herbal Medicines Containing Withania somnifera

“…It is followed by intracavernosal injection of sympathomimetic drug, e.g., phenylephrine. Surgical management in the form of shunting is recommended if conservative management fails or the duration of priapism is more than 48 hours [1,5,6].…”

Molecular Mechanisms and Current Pharmacotherapy of Peyronie’s Disease: A Review

“…Although surgery could correct the penile deformity and provide functional recovery to a certain extent, non-surgical medication, especially for those unwilling or unable to accept surgery, remains an important part of combination regimen for attenuating the fibrotic process, reducing penile deformity and improving intercourse. Moreover, surgery is often a difficult choice for patients, and the risk of surgical complications is also a crucial issue even for an experienced surgeon ( Reddy et al, 2018 ). Thus, pharmacotherapy and even empirical regimen still a very important position in management of PD ( Figure 1 ; Table 1 ).…”

Letter to the editor: Changes in health-related quality of life after radical prostatectomy for prostate cancer: A longitudinal cohort study in Korea

“…Penile prosthesis implantation is considered third-line treatment in males with erectile dysfunction in whom medical treatment is ineffective or unacceptable. In such cases, the implantation of a prosthesis is the only possible treatment to recover the patient's penile erection and to restore the patient's sexual quality of life [45]…”