2010
DOI: 10.1016/j.neulet.2010.04.037
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Role of oxidative stress in animal model of visceral pain

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Cited by 24 publications
(22 citation statements)
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“…15 Catalase activity, in turn, converts H 2 O 2 to water. 23 Furthermore, GPx is an important enzymatic mechanism for the disposal of peroxides, producing water or alcohol and reduced glutathione. 24 Nitric oxide may react with the superoxide radical and form peroxynitrite, a very deleterious nitrogen species, which may lead to lipid and protein peroxidation and damage.…”
mentioning
confidence: 99%
“…15 Catalase activity, in turn, converts H 2 O 2 to water. 23 Furthermore, GPx is an important enzymatic mechanism for the disposal of peroxides, producing water or alcohol and reduced glutathione. 24 Nitric oxide may react with the superoxide radical and form peroxynitrite, a very deleterious nitrogen species, which may lead to lipid and protein peroxidation and damage.…”
mentioning
confidence: 99%
“…Inhibitors of nitric oxide synthase that produces NO reduce both the increased concentrations of NO and some of the pain-related behaviors [30,31]. Vaculin showed colorectal distension as a model of visceral pain using increased oxidative stress in animals, which could be prevented by prior administration of antioxidants [32]. The results in the study also showed that TAC was significantly decreased in SUP of PI-IBS compared to the control group.…”
Section: Discussionmentioning
confidence: 74%
“…It is known that SOD expression may be induced by proinflammatory cytokines, possibly conferring protection to normal tissue during inflammation to maintain the balance between prooxidants and antioxidants in the organism. 37,38 Despite the limited sample of our study, it may be said that the maintenance of SOD activity would be favorable to the organism because this enzyme is responsible for dismutation of O 2…”
Section: Discussionmentioning
confidence: 98%