Role of Osteopontin in Bovines and their Association with Different Traits: A Review

Kumar, Sachin; Mukherjee, Anupama; Kumar, Suresh; Yadav, Alok Kumar; Kumar, Neeraj

doi:10.9735/0975-2862.10.3.370-372

biop

2018

DOI: 10.9735/0975-2862.10.3.370-372

|View full text |Cite

Role of Osteopontin in Bovines and their Association with Different Traits: A Review

Sachin Kumar¹,

Anupama Mukherjee²,

Suresh Kumar³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2020

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Effect of Osteopontin gene variants on milk production traits in Holstein Friesian crossbred cattle of Kerala

Lali¹,

Anilkumar²,

Aravindakshan³

2020

Turk J Vet Anim Sci

View full text Add to dashboard Cite

Osteopontin gene (OPN) is located in the quantitative trait loci (QTL) for milk production traits in bovine chromosome 6. In the present study the impact of cytosine to thymine transition in the intron-4 of OPN gene (g.8514C > T) on milk production traits was analysed in the Holstein Friesian crossbred cattle of Kerala. Genomic DNA was isolated and a fragment of 290 bp enclosing the polymorphic site was amplified and genotyped by restriction fragment length polymorphism (RFLP) using endonuclease, BSeN1. The genetic variants were distributed according to Hardy-Weinberg equilibrium. The T allele was found to be the major one (T/0.76, C/0.24) and the genotype frequencies were TT/0.60, CT/0.32, and CC/0.08. The amplicons of genotypes were sequenced by sangers dideoxy termination technique and confirmed the mutation. Association study using the General Linear Model-Analysis of Variance (GLM-ANOVA) considering marker, season of calving, parity and herd as fixed factors and dairy trait as dependent variable revealed that none of the yield traits (305 day milk yield, peak yield, fat yield, protein yield, solids not fat yield, lactose yield, daily milk yield) or composition traits (fat percent, protein percent, solids not fat percent and lactose percent) of milk production analysed were significantly differed between CT and TT genotyped animals. The OPN gene polymorphism (g.8514C > T) can be suggested for marker assisted selection (MAS) for future breeding programmes for dairy cattle only after extensive association studies.

show abstract

Effect of Osteopontin gene variants on milk production traits in Holstein Friesian crossbred cattle of Kerala

Lali¹,

Anilkumar²,

Aravindakshan³

2020

Turk J Vet Anim Sci

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Role of Osteopontin in Bovines and their Association with Different Traits: A Review

Cited by 1 publication

References 31 publications

Effect of Osteopontin gene variants on milk production traits in Holstein Friesian crossbred cattle of Kerala

Effect of Osteopontin gene variants on milk production traits in Holstein Friesian crossbred cattle of Kerala

Contact Info

Product

Resources

About