Role of omega-3 fatty acids as a treatment for depression in the perinatal period

Rees, Anne-Marie; Austin, Marie‐Paule; Parker, Gordon

doi:10.1111/j.1440-1614.2005.01565.x

Cited by 10 publications

(10 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There was early enthusiasm for omega-3 fatty acids, although most randomized clinical trials to date have failed to show that the active treatment differs from placebo. (Freeman et al, 2006), (Rees, Austin, & Parker, 2005). However meta-analysis for the role of omega-3 fatty acids for maternal MD has been found to be less consistent and further definitive studies are needed (Hosli, Zanetti-Daellenbach, Holzgreve, & Lapaire, 2007) .…”

Section: Discussionmentioning

confidence: 99%

Management of Major Depression in pregnancy: A comparison of approaches by Psychiatrists and Obstetricians and Gynecologists

Jain¹,

Hampton²,

Caples³

et al. 2012

J Behav Health

View full text Add to dashboard Cite

Topic: Management of Major Depression in Pregnancy: A Comparison of Approaches by academic Psychiatrists and Obstetricians and Gynecologists. Purpose: Major Depression (MD) can complicate pregnancy outcome. To manage MD during pregnancy, the American College of Obstetricians and Gynecologists (ACOG) and the American Psychiatric Association (APA) have offered consensual recommendations. This study compares the approaches of academic physicians of these two specialties to manage MD during pregnancy. Methods: A 10 minute survey that assessed individual and self-report practices about managing MD during pregnancy was developed and sent to major academic training programs across the US. Areas assessed include modalities of intervention during mild, moderate, and severe depression, preference for counseling, preference for antidepressant intervention, comparison of use of screening tools between the two specialties, choice of antidepressant and assessment of use of non-pharmacological interventions such as ECT, light therapy and use of alternative medicines such as the Omega three fatty acids. A total of 51 Obstetrics and gynecology training program directors and a total of 18 psychiatry training program directors responded by completing and mailing back the questionnaires. Conclusions: We found that the academic Obstetricians and Gynecologists and the academic Psychiatrists differed in their approach to manage MD during pregnancy under similar circumstances. The two different approaches under similar conditions reflected the level of comfort in their respective practices.

show abstract

Section: Discussionmentioning

confidence: 99%

Management of Major Depression in pregnancy: A comparison of approaches by Psychiatrists and Obstetricians and Gynecologists

Jain¹,

Hampton²,

Caples³

et al. 2012

J Behav Health

View full text Add to dashboard Cite

show abstract

“…A 1% increase in plasma DHA was related to a 59% decrease in risk of depressive symptoms postpartum. 11 Unfortunately, as described earlier, pregnant women's diets are often deficient in DHA, which is unfortunate given fetuses' high need for it. As Rees et al 11 noted, during the last trimester of pregnancy, fetuses accumulate an average of 67 mg per day of DHA.…”

Section: Additional Effects Of Docosahexaenoic Acid In the Perinatal mentioning

confidence: 99%

“…Fish consumption has a similar effect on postpartum depression. Rees et al 11 observed that the rates for postpartum depression in North America and Europe are 10 times those in Taiwan, Japan, Hong Kong, and some regions of China. In a large cross-national ecologic analysis of 41 published studies with more than 14,532 women from 22 countries, 20 Hibbeln noted that postpartum depression was up to 50 times more common in countries with low fish consumption.…”

Section: Omega-3s and Depression In Population Studiesmentioning

confidence: 99%

See 1 more Smart Citation

Long‐Chain Omega‐3 Fatty Acids and Women's Mental Health in the Perinatal Period and Beyond

Kendall–Tackett

2010

J Midwife Womens Health

View full text Add to dashboard Cite

Recent research has shown that depression and a range of physical illnesses, including heart disease, metabolic syndrome, and type 2 diabetes, have an inflammatory etiology. The long-chain omega-3 fatty acids (omega-3s) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are found in fish and fish-oil products, may protect against these illnesses, in part because they lower inflammation. This article reviews the recent research on omega-3s and women's mental health, with a particular focus on the perinatal period. These studies include population studies examining fish consumption and studies testing the efficacy of EPA and DHA as treatments for depression. Although the findings are mixed, the majority of studies indicate that EPA has efficacy in treating depression either alone or in combination with DHA and/or antidepressant medications. The role of DHA alone in mental health is less clear, but it is generally combined with EPA and appears to have a beneficial effect. In moderate doses, EPA and DHA appear safe for pregnant and postpartum women, and they are well tolerated by patients.

show abstract

“…43 The demonstrated correlation between lower gestational seafood consumption and higher rates of postpartum depression 44 suggests that individual v3FA indices may also be a determinant of postpartum mood status. 45,46 Possibly associated with the limited seafood intake in North America, the incidence of postpartum depression is in the range of 12% compared with about 2% in Japan where fish consumption is high 44 (although major cultural differences in the way the two societies are organised may also be important). Furthermore, low DHA in breast milk and maternal red cells, resulting from low gestational intake of EFAs, 47 are commonly found in women with postpartum depression.…”

Section: Maternal and Paediatric Benefits Of Omega-3 Fatty Acid Suffimentioning

confidence: 99%

A fishy recommendation: omega‐3 fatty acid intake in pregnancy

Genuis

2007

BJOG

View full text Add to dashboard Cite

Role of omega-3 fatty acids as a treatment for depression in the perinatal period

Abstract: There is a relative lack of knowledge about the safety of standard antidepressants in the perinatal period. There is a clear need for more research into alternative treatments, such as omega-3 fatty acids, in the management of depression in the perinatal period.

Cited by 10 publications

References 55 publications

Management of Major Depression in pregnancy: A comparison of approaches by Psychiatrists and Obstetricians and Gynecologists

Management of Major Depression in pregnancy: A comparison of approaches by Psychiatrists and Obstetricians and Gynecologists

Long‐Chain Omega‐3 Fatty Acids and Women's Mental Health in the Perinatal Period and Beyond

A fishy recommendation: omega‐3 fatty acid intake in pregnancy

Contact Info

Product

Resources

About