Role of OCT in the diagnosis and follow up of diabetic macular edema

Panozzo, Giacomo; Gusson, Elena; Parolini, Barbara; Mercanti, Andrea

doi:10.1080/08820530390897882

Cited by 20 publications

(29 citation statements)

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“…Fluorescein angiography can explain some dynamics of the pathophysiological aspects of DMO, whereas OCT shows us its anatomical features, such as the extent of thickening and the retinal layer(s) involved. Studies on morphological changes on DMO have revealed three main categories of changes: sponge-like swelling; cystoid patterns, and serous detachment (Otani et al 1999;Panozzo et al 2003). (Otani et al 1999).…”

Section: Introductionmentioning

confidence: 99%

Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

Soliman

Sander

Hasler

et al. 2008

Acta Ophthalmologica

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ABSTRACT.Purpose: To study the relationship between intraretinal optical coherence tomography (OCT) and fluorescein angiography (FA) findings in eyes with diabetic macular oedema (DMO). Methods: We carried out a retrospective observational case series. Thirty eyes with previously untreated DMO underwent FA and OCT. The same ETDRS template was overlaid on the FA images in order to compare OCT and FA. Transfoveal linear high-resolution OCT scans (at the 0-and 90-degree meridians) and FA pictures were compared according to the ETDRS rings. Results: Six distinct patterns of intraretinal changes in OCT correlated with changes in FA: (a) focal angiographic leakage did not correspond to any obvious intraretinal abnormality in OCT in four eyes; (b) localized thickening of the outer nuclear layer in OCT corresponded to focal leaking microaneurysm (focal oedema) in FA in 11 eyes; (c) diffuse thickening of the outer nuclear layer in OCT corresponded to diffuse angiographic leakage in 21 eyes; (d) cystoid expansion of the outer nuclear layer was found in seven eyes with a petaloid angiographic pattern of leakage; (e) cystoid expansion of the inner nuclear layer was found in relation to honeycomb angiographic oedema in five eyes, and (f) serous detachment of the fovea in OCT did not correspond to any distinct finding in FA in four eyes. Conclusions: Intraretinal abnormalities found in OCT correlate systemically with changes in FA. Very early DMO morphological changes may be seen better with FA than with OCT. Serous detachment of the fovea is seen in OCT, but not in FA. The combination of OCT and FA is useful in facilitating understanding of the pathophysiological changes that occur in DMO.

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Section: Introductionmentioning

confidence: 99%

Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

Soliman

Sander

Hasler

et al. 2008

Acta Ophthalmologica

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“…Central foveal thickness is an OCT parameter that is usually used in the control of different diseases such as diabetic macular oedema,21 age-related macular degeneration22 or central serous chorioretinopathy 23. Recently, Lorenzo et al 15 used central foveal thickness in patients with serous retinal detachment associated with dome-shaped macula and found that this measurement remained stable over 12 months of follow-up.…”

Section: Discussionmentioning

confidence: 99%

Comparison of long-term clinical evolution in highly myopic eyes with vertical oval-shaped dome with or without untreated serous retinal detachment

et al. 2018

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“…[10][11][12] Spectral domain optical coherence tomography (SD-OCT) allows high-resolution imaging of the macula and permits visualization of retinal disease on a microscopic level. 4,5,[7][8][9][13][14][15] Identification of novel anatomical and morphologic microscopic findings by SD-OCT imaging has permitted greater insight into the underlying mechanisms of macular disease.…”

Section: Eration [Amd]mentioning

confidence: 99%