“…This was notably the case with the question, ‘What type of diet/vitamin supplementation can help prevent myopia/myopia progression?’ (Question 11, ‘Treatment and Prevention’ domain, Supplementary Tables S1a–c ). Despite ongoing research yielding inconclusive evidence about the correlation between diet, supplements, and the prevention of myopia or myopia progression, 36 , 37 , 38 , 39 all three LLM-Chatbots recommended the consumption of supplements such as omega-3 fatty acids ( Supplementary Tables 1a–c, 4b and c ). These observations highlight the risk of LLM-Chatbots providing misinformation to unsuspecting patients, while indicating their limited ability to identify and rectify such instances.…”