Role of Neutrophil CD64 as an Emerging Biomarker in the Evaluation of Neonatal Sepsis

Ahmed, Mansoor

doi:10.15406/icpjl.2017.04.00107

ICPJL

2017

DOI: 10.15406/icpjl.2017.04.00107

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Role of Neutrophil CD64 as an Emerging Biomarker in the Evaluation of Neonatal Sepsis

Mansoor Ahmed¹

Abstract: Background: Early diagnosis and treatment of neonatal sepsis may be helpful in decreasing neonatal mortality. Neonatal sepsis is considered as one of the major causes of morbidity and mortality.

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2024

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“…However, the opposite was documented by Paul et al,[13] EOS was observed more (65%) than LOS (35%). https://ejmr.journals.ekb.eg/ consistent with those of Halil et al's[17] study on septic neonates in Turkey, which https://ejmr.journals.ekb.eg/…”

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Diagnostic Value of Interleukin-33 in Neonatal Sepsis

Salem,

Farag,

Ahmed

et al. 2024

Egyptian Journal of Medical Research

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Background: Most infant deaths are attributed to neonatal sepsis. Reduced morbidity and mortality can be achieved with prompt diagnosis. Due to the disease's rapid course, accurate utilization of disease-specific biomarkers is crucial for timely diagnosis and treatment. Aim and objective: This study aimed to find out serum IL33 levels in neonates with sepsis and to investigate its role in the identifying of neonatal sepsis. Methods: Case-control research was performed on 45 cases diagnosed with neonatal sepsis with positive blood cultures and 45 healthy neonates as controls. A peripheral blood sample was taken from the patients and controls then IL33 levels were measured by ELISA. Results: In newborn sepsis individuals, serum IL 33 levels were significantly greater than in healthy controls (203.963.1vs.127.430.5 ng/ml, respectively: p less than 0.001). Serum IL33 levels were significantly positively correlated with CRP levels in neonatal sepsis patients. IL33 is increased in survivor than in non-survivor cases. Conclusion: Elevated levels of interleukin 33 strongly correlate with neonatal sepsis so it might function as a reliable a diagnostic indicator for neonatal sepsis.

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confidence: 69%

Diagnostic Value of Interleukin-33 in Neonatal Sepsis

Salem,

Farag,

Ahmed

et al. 2024

Egyptian Journal of Medical Research

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Role of Neutrophil CD64 as an Emerging Biomarker in the Evaluation of Neonatal Sepsis

Abstract: Background: Early diagnosis and treatment of neonatal sepsis may be helpful in decreasing neonatal mortality. Neonatal sepsis is considered as one of the major causes of morbidity and mortality.

Cited by 1 publication

References 17 publications

Diagnostic Value of Interleukin-33 in Neonatal Sepsis

Diagnostic Value of Interleukin-33 in Neonatal Sepsis

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