Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery disease

Sabharwal, Nikant; Lahiri, Avijit

doi:10.1136/heart.89.11.1291

Cited by 62 publications

(39 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For statistical analysis, a commercially available Windows-based software product was used (SPSS 12.0. 1,2003).…”

Section: Discussionmentioning

confidence: 94%

“…The detailed assessment of myocardial perfusion defects can be crucial in the evaluation of the functional or hemodynamic impact of a given coronary artery lesion [1]. It has also been shown that the occurrence of an MI, even if it is asymptomatic, is associated with an increased risk of future ischemic events and an increased cardiac mortality [2].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

et al. 2005

View full text Add to dashboard Cite

To assess the diagnostic accuracy of 16-detector-row computed tomography (16DCT) of the heart in the assessment of myocardial perfusion and viability in comparison to stress perfusion magnetic resonance imaging (SP-MRI) and delayed-enhancement magnetic resonance imaging (DE-MRI). A number of 30 patients underwent both 16DCT and MRI of the heart. Contrast-enhanced 16DCT data sets were reviewed for areas of myocardium with reduced attenuation. Both CT and MRI data were examined by independent reviewers for the presence of myocardial perfusion defects or myocardial infarctions (MI). Volumetric analysis of the hypoperfusion areas in CT and the infarct sizes in DE-MRI were performed. According to MRI, myocardial infarctions were detected in 11 of 30 cases, and perfusion defects not corresponding to an MI were detected in six of 30 patients. CTA was able to detect ten of 11 MI correctly (sensitivity 91%, specificity 79%, accuracy 83%), and detected three of six hypoperfusions correctly (sensitivity 50%, specificity 92%, accuracy 79%). Assessing the volume of perfusion defects correlating to history of MI on the CT images, a systematic underestimation of the true infarct size as compared to the results of DE-MRI was found (P<0.01). Routine, contrast-enhanced 16-detector row CT of the heart can detect chronic myocardial infarctions in the majority of cases, but ischemic perfusion defects are not reliably detected under resting conditions.

show abstract

“…For statistical analysis, a commercially available Windows-based software product was used (SPSS 12.0. 1,2003).…”

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Myocardial perfusion imaging (MPI) possesses an essential role as a gatekeeper to discriminate those lesions needed to be invasively approached, because unnecessary invasive treatment for coronary stenosis with normal perfusion may lead to unexpected adverse events [1]. In such perspective, many studies to establish the way to find the "culprit" vessel or lesion have been conducted and various assignments of vascular territory to myocardial segments have been introduced [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Myocardial Blood Flow and Flow Reserve in Proximal and Mid-to-Distal Lesions of Left Anterior Descending Artery Measured By N-13 Ammonia PET/CT

Cho

Kim

Cho

et al. 2013

Nucl Med Mol Imaging

View full text Add to dashboard Cite

Purpose The purpose of this study is to compare the myocardial blood flow (MBF) and flow reserve (MFR) between proximal and mid-to-distal lesions of the left anterior descending artery (pLAD and mdLAD, respectively) using N-13 ammonia positron emission tomography/computed tomography (PET/CT). Methods Subjects were 11 patients (six men and five women, mean age 64.5 years) with known coronary artery disease (CAD) involving LAD studied by N-13 ammonia PET/CT. They were divided into two groups by the location of stenotic lesions, i.e. pLAD versus mdLAD. Global and regional MBF and MFR were measured and compared. Characteristics of perfusion defects including the number of involved segments, basal area involvement, location, size, and shape were also compared between the two groups. Results The regional MFR in mid-anterior segment was significantly lower in pLAD group (1.80±0.35 vs 2.76±1.13 for pLAD and mdLAD groups, respectively, p=0.034), while global MFR was not different (2.10±1.10 vs 2.34±0.84).Both stress and rest MBF in LAD territories were not different in both groups. The size of the perfusion defects were significantly larger in pLAD group (44.0±11.5 % vs 21.1±15.8 %, p=0.041). Other characteristics such as location, basal area involvement, and shape were not significantly different between two groups. Conclusions The proximal lesion makes lower MFR in the mid-anterior segment and larger perfusion defect in the LAD territory but comparable MBF compared with mdLAD lesion.

show abstract

“…While the high risk patients are great benefit of coronary angiography and revascularization procedures, low risk patients are followed-up with conservative treatments [21]. increase to improve survival in the larger defect areas ("Summed Stress Score"> 9) [22].…”

Section: Mineral Watermentioning

confidence: 99%

The Effects of Mineral Water Drinking and Extra-abdominal Pressure in Elimination of Attenuation Artifacts on Myocardial Perfusion SPECT

Bati¹,

Kekilli²,

Koksal³

et al. 2015

Med-Science

View full text Add to dashboard Cite

show abstract

Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery disease

Cited by 62 publications

References 57 publications

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

Assessment of myocardial perfusion and viability from routine contrast-enhanced 16-detector-row computed tomography of the heart: preliminary results

Myocardial Blood Flow and Flow Reserve in Proximal and Mid-to-Distal Lesions of Left Anterior Descending Artery Measured By N-13 Ammonia PET/CT

The Effects of Mineral Water Drinking and Extra-abdominal Pressure in Elimination of Attenuation Artifacts on Myocardial Perfusion SPECT

Contact Info

Product

Resources

About