Role of multidetector computed tomography (MDCT) in patients with ovarian masses

Mubarak, Fatima; Alam, Muhammad Shahbaz; Akhtar, Waseem; Hafeez, Saima; Nizamuddin, Noureen

doi:10.2147/ijwh.s15501

Cited by 13 publications

(14 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of CT in our study compared to other studies in literature (Table 7) showed a higher sensitivity, comparable to the study by Mubarak et al 19 Although our study showed a very low specificity of 46% because of the high number of false positives which may be due to non-specific inflammatory changes within the tumour, reactive lymphadenitis appearing as enlarged lymph nodes on CT, which were reported as possible malignancy, which changes the stage of disease. And also lack of extensive retroperitoneal and paraaortic lymph node dissection also would have contributed to the low specificity.…”

supporting

confidence: 83%

Comparison of CA-125, conventional ultrasound and CT imaging in diagnosis and staging of ovarian cancer correlated with surgico-pathological findings

Moideen

Hebbar

Rai

et al. 2014

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

supporting

confidence: 83%

Comparison of CA-125, conventional ultrasound and CT imaging in diagnosis and staging of ovarian cancer correlated with surgico-pathological findings

Moideen

Hebbar

Rai

et al. 2014

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

“…Radiologic assessments help decide the surgeon about whether the therapeutic approach needs to be by a general gynaecologist in a local centre or need to be referred to a cancer centre. 16 Ultrasound is the first choice of investigation to evaluate adnexal pathologies; however, quite often it is unable to differentiate nature of the lesion and asks for further imaging. MDCT can help in characterizing masses and features pertaining to benignity and malignancy can be evaluated.…”

Section: Discussionmentioning

confidence: 99%

“…MDCT can help in characterizing masses and features pertaining to benignity and malignancy can be evaluated. 16 Mature cystic teratomas, also known as dermoids, are benign germ cell tumors most commonly seen in women of reproductive and are bilateral in 10% to 25% of cases. Although dermoids can occur at any age, but they are commonly seen at younger age group than do epithelial tumors and are the most common ovarian tumors in children.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography features of benign adnexal mass lesions

Khalda

Mandal

Rahman

2020

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Adnexal masses originating from gynaecologic and nongynecologic sources may be benign or malignant. The objective of this study was to describe multi-detector computed tomography features of benign adnexal masses for diagnostic accuracy and disease understanding.Methods: Study retrospectively evaluates the multidetector computed tomography features of benign adnexal mass lesions, which were referred for MDCT examination with a primary diagnosis of adnexal masses on clinical or USG. Patients who underwent MDCT and subsequently underwent surgery and proved to benign adnexal mass lesion on histopathological examination were included in this study.Results: Forty five percent benign adnexal mass were in the age group of 36-50 years followed by 32.7% in the age group of 21-35 years. Common presenting symptoms of benign adnexal masses were pain abdomen or pelvic pain (65.5%) followed by mass abdomen (42%) while in one fourth of the patients it was asymptomatic and detected as incidental finding. Pathologic diagnosis of most common benign adnexal mass detected were serous cyst adenoma (54.5%), followed by mature cystic teratoma (18.2%), mucinous cyst adenoma (14.5%) and par ovarian cyst (9.1%). Benign ovarian mass had a characteristic CT appearance of cystic lesion (83.6%), unilocular (65.5%) with regular/well defined and thin wall (83.6%) with occasional septations (21.8%) and papillary projections (14.5%). Ascitis (5.5%) was an uncommon finding of a benign adnexal mass lesion. Computed tomography was most accurate to characterize mature cystic teratoma with a typical cystic lesion having fat deposition and calcifications. Serous cyst adenoma had a CT appearance of thin walled cyst mass with no septations or solid component. Mucinous cyst adenoma ovary had a characteristic multilocular cystic lesion with different fluid attenuation and thin septations. Endometrioma had a variable CT appearance with uni or multilocular cystic lesion and hyperdense lesion with focal calcifications.Conclusions: Multi detector computed tomography may provide accurate and valuable diagnostic information about benign nature of an adnexal mass lesion.

show abstract

“…On CT scan, masses can be characterized and features pertaining to benignity and malignancy can be observed. 21 Patients with ovarian cancer present with nonspecific symptoms. The most common symptoms reported by women with ovarian cancer are pelvic or abdominal pain; increased size of the abdomen.…”

Section: Discussionmentioning

confidence: 99%

Role of multi-detector computed tomography in the detection and differentiation of adnexal mass lesions

Khalda

Rahman

2019

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: The objective of this study was to evaluate the role of multi-detector computed tomography (MDCT) in the detection and differentiation of adnexal masses using post-operative histopathology findings as the gold standard.Methods: One hundred and forty five cases that were referred with a primary diagnosis of adnexal masses on clinical or USG examination were evaluated by MDCT in the Department of Radiodiagnosis from January 2013 to December 2013. One hundred twelve cases subsequently underwent surgical exploration and histopathological examination, which was used as a control for the evaluation of MDCT findings, were included in this study.Results: Majority (54.5%) of the patients were in the age group of 31-50 years. MDCT detected adnexal masses as malignant in 56 cases, while in other 56 cases it read adnexal masses as benign. Final histopathology revealed adnexal masses in 57 (51%) cases as malignant while in 55 (49%) cases as benign. There were three cases which on MDCT appeared as malignant were subsequently found to be benign in histopathology. Similarly there were four cases which on MDCT appeared as benign were subsequently proved to malignant in histopathology. The sensitivity, specificity, Positive predictive value and negative predictive value of MDCT for diagnosing a malignant adnexal mass was 93.0%, 94.5%, 94.6% and 92.8% respectively. MDCT findings more predictive of malignancy were solid or cystic-solid mass, necrosis in a solid lesion, cystic lesion with thick, irregular walls or septa, and/or with papillary projections. The presence of ascites, peritoneal metastases, and lymphadenopathy were also helpful to confirm malignancy.Conclusions: MDCT is an excellent and accurate non-invasive modality in the detection and characterization of adnexal masses from benign and malignant

show abstract

Role of multidetector computed tomography (MDCT) in patients with ovarian masses

Cited by 13 publications

References 18 publications

Comparison of CA-125, conventional ultrasound and CT imaging in diagnosis and staging of ovarian cancer correlated with surgico-pathological findings

Comparison of CA-125, conventional ultrasound and CT imaging in diagnosis and staging of ovarian cancer correlated with surgico-pathological findings

Computed tomography features of benign adnexal mass lesions

Role of multi-detector computed tomography in the detection and differentiation of adnexal mass lesions

Contact Info

Product

Resources

About