Role of Left Ventricular Dyssynchrony in Predicting Remodeling after ST Elevation Myocardial Infarction

Abstract

LV dyssynchrony is a strong predictor of LV remodeling after acute myocardial infarction (AMI). It could be useful in risk stratification of patients after AMI.

Prognostic Value of Speckle Tracking Echocardiography in Patients with ST‐Elevation Myocardial Infarction Treated with Late Percutaneous Intervention

“…4 The frequency of LVr in our study was comparable to results recently published 10,18 in which investigators found that 22-33% of patients presented with remodeling within 6 months of an AMI treated with pPCI. LV remodeling post-AMI is an important precursor for the development of heart failure, and it is an important predictor of mortality.…”

Systolic Papillary Muscle Dyssynchrony Predicts Recurrence of Mitral Regurgitation in Patients with Ischemic Cardiomyopathy (ICM) Undergoing Mitral Valve Repair

“…Cardiac dyssynchrony (DYS) is associated with functional deterioration and poor prognosis in advanced systolic heart failure and is an important determinant of postoperative outcome in patients with severe LV dysfunction . Furthermore, DYS is a strong predictor of LV remodeling after acute myocardial infarction …”

“…5 Furthermore, DYS is a strong predictor of LV remodeling after acute myocardial infarction. 6 Two-dimensional (2D) strain imaging based on novel speckle-tracking echocardiography (STE) is a relatively new tool to define regional 1 The first two authors equally contributed to the article. myocardial strain and to quantify dyssynchrony based on a more robust technique and avoiding angle of incidence.…”

Left Ventricular Dyssynchrony Is an Early Manifestation of Heart Involvement in Sickle Cell Anemia

“…Ventricular dyssynchrony is defined as loss of contraction coordination within or between ventricles and is thought to develop in failing heart. Abnormality of the timing of the events during cardiac cycle leads to pump inefficiency and energy expenditure . Dyssynchrony was first emphasized in the early studies in systolic HF patients with low EF and wide QRS complex, however, 1/3 of HF patients with a narrow QRS complex were found to exhibit substantial mechanical dyssynchrony as well .…”

“…Abnormality of the timing of the events during cardiac cycle leads to pump inefficiency and energy expenditure. 6,17 Dyssynchrony was first emphasized in the early studies in systolic HF patients with low EF and wide QRS complex, however, 1/3 of HF patients with a narrow QRS complex were found to exhibit substantial mechanical dyssynchrony as well. [18][19][20][21][22] Recently, systolic dyssynchrony was not only detected in the patients with symptoms of HF and preserved EF 7,23 but also in hypertension, diabetes mellitus, acute myocardial infarction, and hypo-and hyperthyroidism.…”