Role of laparoscopy in the diagnosis of peritoneal tuberculosis in endemic areas

Guirat, Ahmed; Affes, Najmeddine; Rejab, H.; Trigui, H.; Amar, Mohamed Ben

doi:10.1684/mst.2014.0420

Cited by 8 publications

(20 citation statements)

References 36 publications

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“…AFB smear, cultures and GeneXpert have a low sensitivity, <5%, 45–69% and 18% respectively [ 7 ]. Peritoneal biopsy by laparoscopy (for AFB smear, culture, molecular and pathology tests) may be required to establish the diagnosis [ 61 ]. The peritoneum has the appearance of millet seeds.…”

Section: Frequent Locations Of Eptmentioning

confidence: 99%

What pulmonologists need to know about extrapulmonary tuberculosis

Natali

Cloatre

Brosset

et al. 2020

Breathe

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Section: Frequent Locations Of Eptmentioning

confidence: 99%

What pulmonologists need to know about extrapulmonary tuberculosis

Natali

Cloatre

Brosset

et al. 2020

Breathe

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“…Our findings further highlight the reported low sensitivity rates of acid-fast bacilli and Ziehl-Neelsen staining in detection of Tubercle bacilli in ascitic fluid [24][25][26], and the poor sensitivity and specificity of Gene expert in detection of abdominal TB from ascitic fluid samples [27]. The diagnosis of peritoneal tuberculosis in our case, like other related cases [17,18] was made through histological examination of intraoperative collected tissue samples, further stressing the need of pathological examination of samples as the gold standard for definitive diagnosis of peritoneal tuberculosis [28,29] Abdominal tuberculosis is generally responsive to medical treatment. Isoniazid, rifampin, pyrazinamide, ethambutol, and streptomycin are the five common first line medication for treatment of Tuberculosis with treatment duration consisting of a four-drug regimen administered for 2 months then continuation of treatment with rifampin and isoniazid for 4 or more months [30].…”

Section: Discussionmentioning

confidence: 68%

Extensive surgery for peritoneal tuberculosis, an ongoing diagnostic challenge in resource limited setup

Kiritta¹,

Mrisho²,

Mbulwa³

et al. 2021

J Clin Images Med Case Rep

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Background: Peritoneal Tuberculosis is an abdominal form of Tuberculosis that affects the peritoneal cavity and enclosed organs. Clinical presentation of this rare form of extrapulmonary tuberculosis resembles that of advanced ovarian cancer and may results in unnecessary extensive surgery especially in resource limited setting. Case presentation: A case of a 36 years old prisoner who presented to us with gradual onset of abdominal distension for one-month, mild abdominal pain and noticeable progressive weight loss. Physical examination revealed she was underweight, afebrile and had a healed sub umbilical median incision scar on a glossily distended abdomen with positive fluid thrill and shifting dullness. She was HIV negative, anemic and had marked elevation of Cancer Antigen 125 marker. Abdominal ultrasound scan showed ascites with multiple cysts originating from the left iliac fossa and the abdominal pelvic CT scan showing left ovarian cyst, ascites of 3 litres and diffuse peritoneal carcinomatosis. Advanced ovarian cancer was suspected and intra-operatively 2.5 liters of straw colored ascitic fluid was found, the bowels and the omentum were covered with diffuse intestinal nodules and multiple inclusion cysts occupying the pelvic cavity. Histopathological analysis of sampled tissues revealed Peritoneal Tuberculosis. Conclusion: Peritoneal tuberculosis shares similarities in presentation to advanced ovarian cancer and should be ruled out in a woman suspected of ovarian cancer before proceeding with surgery. For proper differentiation of the two, histopathological analysis of sampled tissue through frozen section biopsy is the preferred approach in resource limited setup where laparoscopic biopsy or ultrasound guided biopsy is not feasible.

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“…A recent study of 43 cases of PTB showed that initial screen for mycobacterium and final cultures in the ascitic fluid were negative in all the patients. 1 However, surgically obtained peritoneal biopsies were positive in all 43 patients for mycobacterium.…”

Section: Case Reportmentioning

confidence: 91%