Role of IVIM MRI in staging and restaging of rectal cancer

Abstract

Background: IVIM is a noninvasive method that analyses both the mobility of free water particles and the perfusion generated by microcirculation in vivo using a biexponential mathematical model with varied b values . Aim: To evaluate Role of IVIM MRI in staging and restaging of rectal cancer. Methodology: A comprehensive search was conducted for papers that looked into the role of IVIM MRI in rectal cancer staging and restaging. The pooled specificity, sensitivity, constructed summary receiveroperating characteristic characteristics curve, and positive likelihood ratio were estimated after the data was extracted. Results: After a full-text review, 11 studies were found to be qualified. Specificity and sensitivity were 81 percent (0.83-0.91) and 86 percent (0.77-0.87), respectively, in the pooled data. The area under the receiver operating characteristic curve using summarized receiver operating characteristics was 0.97. Conclusions: According to this meta-analysis, IVIM MRI is an accurate, noninvasive diagnostic tool for staging and restaging rectal cancer.