“…Consequently, 11 unique studies characterizing a total of 27 885 unique patients (median age, 65 years [range, 58.5-74.5 years]; 74.4% male and 25.6% female) were selected into our meta-analysis. 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 The baseline characteristics of included studies are summarized in Table 1 , and quality assessment for included trials is presented in eTable 1 in the Supplement . Outcome data of included studies were extracted and are detailed in eTable 2 in the Supplement .…”